268203-93-6 Udenafil

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price: USD 1000.0000

1 Kilogram

FOB Price: USD 1000.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,T/T

Keywords

268203-93-6 Udenafil Udenafil

Quick Details

Appearance:white powder
Application:pharma
PackAge:as clients needs
ProductionCapacity:1|Metric Ton|Day
Storage:RT
Transportation:sea

Superiority:

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:

1.Noble Metal Catalysts (Pt.Pd...)

2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

3.OLED intermediates (Fluorene,Carbazole,Boric acid...)

4.Customs Synthesis

Our advantage:

1. Higest quality and good package

2.Fast delivery

3.Better payment term

4.Fast response to customer within 6 hours

5.Good business credit in Europe ,US ,Japan ,Korea

Anyway ,if you need any chemicals from China ,Henan Tianfu can help you

Details:

Udenafil Chemical Properties
Boiling point    697.0±65.0 °C(Predicted)
density    1.35
pka   11.07±0.50(Predicted)
Safety Information
MSDS Information
Udenafil Usage And Synthesis
Description   Udenafil is the fourth in a class of drugs targeting the inhibition of the enzyme phosphodiesterase 5 (PDE5) for the treatment of erectile dysfunction. Inhibition of PDE5 results in the increase in endogenous cyclic guanosine monophosphate (cGMP) concentrations in the penile corpus cavernosum. cGMP induces smooth muscle cell relaxation and subsequent increased blood flow leading to a sustainable erection. Udenafil is a potent antagonist of human PDE5 with an IC50 of 8.25nM and a comparable selectivity profile as sildenafil for the other PDEs. Unlike tadalafil, it does not inhibit PDE11, which has been implicated in myalgia and testicular toxicity. Furthermore, udenafil produced up to a 91% vaginal penetration success rate and up to a 67% intercourse completion rate compared to a 29% completion rate by placebo. Overall patient satisfaction, measured by a standard global assessment question, was 86% compared to only 26% in the placebo group. The most frequently recorded adverse events were mild-to-moderate facial flushing and headache.
Chemical Properties   Off-White Solid
Originator   Dong-A (South Korea)
Uses   An oral phosphodiesterase 5 inhibitor used for the treatment of erectile dysfunction.
Brand name   Zydena

View All

Visit Store