SB 203580 SB 203580 manufacturer/supplier 152121-47-6
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Hangzhou Jinlan Pharm-Drugs Technology Co., Limited is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l Airport, the transportation and production environment are excellent.
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SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27. At low concentrations, it does not inhibit JNK activity.
Chemical Name |
4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine |
Synonyms |
PB 203580;4-(4-(4-Fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine;4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(pyridin-4-yl)-1H-imidazole;RWJ 64809;Pyridine,4-(5-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl);Expand |
CAS No. |
152121-47-6 |
Molecular Formula |
C21H16FN3OS |
Molecular Weight |
377.43500 |
PSA |
77.85000 |
LogP |
5.54790 |
MDL number |
MFCD00922198 |
Appearance & Physical State |
White solid |
Density |
1.42 g/cm3 |
Boiling Point |
615.6ºC at 760 mmHg |
Melting Point |
249 - 250ºC |
Flash Point |
326.1ºC |
Refractive Index |
1.714 |
Vapor Pressure |
2E-14mmHg at 25°C |
Safety Statements |
26-39 |
HS Code |
2818200000 |
Risk Statements |
R22; R41 |
Hazard Codes |
Xn |
Signal Word |
Danger |
Hazard Declaration |
H302; H318 |
Caution Statement |
P280; P305 + P351 + P338 |
Symbol |
GHS05, GHS07 |
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