in China Lovastatin...

in China Lovastatin 75330-75-5 for sale Lovastatin global trader
in China Lovastatin 75330-75-5 for sale Lovastatin global trader
in China Lovastatin 75330-75-5 for sale Lovastatin global trader
in China Lovastatin 75330-75-5 for sale Lovastatin global trader
in China Lovastatin 75330-75-5 for sale Lovastatin global trader

in China Lovastatin 75330-75-5 for sale Lovastatin global trader

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 55.0000 -70.0000

  • Min.Order :1 Kilogram
  • Purity: 5%
  • Payment Terms : D/A,D/P,T/T,

Keywords

in China Lovastatin 75330-75-5 for sale Lovastatin global trader

Quick Details

  • Appearance:Red Fine Powder
  • Application:1. Food additives, coloring agents (meat products, juice, color wine, jam, beverage, candy, pastry, soy sauce, health vinegar, etc.; 2. Pharmaceutical coloring agents, functional health products; 3.
  • PackAge:1kg with double plastic container inside/Aluminum foil bag outside. 25kg with double plastic container inside/Fiber drum outside.
  • ProductionCapacity:100000|Kilogram|Year
  • Storage:Stored in a clean, cool, dry area; keep away from strong
  • Transportation:Express, sea, land, air

Superiority:

in China Lovastatin 75330-75-5 for sale Lovastatin global trader

Natural statin compounds is has very similar structure with each other. They have the same poly-ketone portion of hydroxy-hexahydro-cyclic with different side chains attached to C8 (R1) and C6 (R2) bits. R1 of lovastatin is methylbutyryl, R2 is 6-α-methyl; mevastatin has no 6-position methyl. Natural statin compounds are all in the form of lactone. They need to be hydrolyzed to acidic form before becoming active. Fully synthetic statin compound, although is structurally different from the natural statins but still have a lactone ring-opening portion which is the common structure of all statins which is responsible for its competitive inhibition on HMG-CoA reductase.

Lovastatin is a statin natural product isolated from numerous sources including the Pleurotus ostreatus oyster mushroom, demonstrating hypocholesterolemic and antiproliferative properties. Lovastatin inhibits HMGCR (3-hydroxy-3-methylglutaryl coenzyme A reductase), blocking the enzyme-catalyzed transformation of 3-hydroxy-3-methylglutaryl CoA into mevalonate. The biosynthesis of cholesterol requires mevalonate as a building block and elimination of mevalonate generation subsequently interrupts cholesterol synthesis, leading to a reduction of circulating low-density lipoproteins. Lovastatin demonstrates arrest of the cell cycle at the G1 phase in bladder carcinoma T24 cells expressing activated p21ras oncoprotein - the posttranslational isoprenylation of the p21ras with mevalonate is crucial for translocation and membrane adhesion of the protein, and blockade of this modification by Lovastatin-induced depletion of cellular mevalonate leads to suspension of cell progress. The signaling activity of epidermal growth factor (EGF) and insulin-like growth factor (IGF-I) are similarly affected by impairment of mevalonate-dependent protein prenylation. Induction of apoptosis by Lovastatin in malignant mesothelioma cells is also ascribed to the inhibition of mevalonate synthesis and posttranslational protein modifications. Lovastatin is a substrate of CYP and Mdr-1.

Alternate Name Mevinolin; Mevacor; Monacolin K; 6-α-Methylcompactin; MK-803
Appearance White solid
CAS # 75330-75-5
Molecular Formula C??H??O?
Molecular Weight 404.54
Purity ≥98% by HPLC
Solubility DMSO (25 mg/ml) or Ethanol (30 mg/ml)
SMILES CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
InChi InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
InChi Key PCZOHLXUXFIOCF-BXMDZJJMSA-N
PubChem CID 53232
MDL Number MFCD00072164
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack

Details:

High Quality 100% Natural halal kosher certificate Red Yeast Rice Extract Powder 5% Lovastatin

Red kojic rice is milled as raw materials, adopt modern biological engineering technology to isolate the high quality red by liquid submerged fermentation of aspergillus refined but become, is a kind of pure natural, high safety, food additives are beneficial to human body health.Moreover, this product has bright color, pure color, full color and good photothermal stability. It is an ideal colorant for natural green food.

Product Name Red Yeast Rice Extract Lovastatin
Active ingredients Lovastatin: 5%
Specification 2% 5% 
Grade Medical / Food/Cosmetic Grade
Application Food coloring, raw materials for eye health products
Test Method HPLC
Shlfe life 24months

 

 

 

 

 

 

 

 

 

 

 

 

 

Product Function

1. Invigorate the spleen and eliminate food, invigorate the blood and remove blood stasis;
2. Lowering blood lipids, lowering total cholesterol, reducing enzyme inhibitors, directly inhibiting hng-coa reductase, and blocking cholesterol synthesis;
3. Lovastatin can effectively reduce the serum cholesterol content of patients with mixed familial and non-familial hypercholesterolemia.

Product Application

1. Food additives, coloring agents (meat products, juice, color wine, jam, beverage, candy, pastry, soy sauce, health vinegar, etc.;
2. Pharmaceutical coloring agents, functional health products;
3. Cosmetics category.

Company Profile

Product Packing And Transportation

FAQ

Q1: Can I get some samples
A: Yes, free samples(10-20g or enough to detection) are available for most of our products, you only need to pay the shipping cost.


Q2: How to confirm the quality before orders
A: Two ways, either by free samples, or send us the detailed specifications, we will arrange the production as per your requirement.

Q3: What's your MOQ
A: Normally 1 kg, but smaller quantity is also acceptable for some special products.

Q4: How about discount
A: Mainly based on quantity, also some promotional products with special discount from time to time.

Q5. What's the delivery lead time
A: 2-3 working days after payment.

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