Deoxycholic Acid On Sale Deoxycholic Acid powder 83-44-3 Good Supplier In China Deoxycholic Acid

Superiority:

Deoxycholic Acid On Sale Deoxycholic Acid powder 83-44-3 Good Supplier In China Deoxycholic Acid

Excess submental fat (SMF)[i.e. fat under the chin/neck] can make people feel older and unattractive. It can develop as a consequence of the aging process, genetic predisposition or lifestyle choices, and generally does not improve with weight reduction measures. Surgical techniques, such as neck-lifts and liposuction, are effective in removing unwanted SMF, but are invasive procedures with certain risks and drawbacks (e.g. bruising, swelling, scarring and painful/prolonged recovery periods), and] some individuals may not wish, or be suitable, to undergo them. Less invasive modalities to reduce SMF include ultrasound, laser procedures and the injection of agents with fat-reducing properties, although the efficacy of these treatments has not been established in robust randomized trials. Historically, fat-reducing formulations have typically comprised phosphatidylcholine solubilized with deoxycholic acid, although their efficacy in reducing localized fat, such as that of the submental region, has been shown in vitro to be largely due to the deoxycholic acid component.

Deoxycholic acid has been used in a modified procedure to recover 40-80% of a protein from a 1 µg/mL solution. It forms complexes with fatty acid. Used as an emulsifying agent in food, a precursor in the synthesis of cortisone, and a gallbladder stimulant. It has been used to study assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.

Deoxycholic acid is a secondary bile acid involved in the emulsification and solubilization of dietary fat. A 10 mg/mL injectable solution of chemically synthesized deoxycholic acid is indicated in various countries, including the USA (KybellaTM) and several within Europe/the EU (BelkyraTM) to improve the appearance of moderate to severe submental convexity or fullness associated with SMF in adults, where it is currently the only approved minimally invasive treatment for submental contouring.