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117704-25-3 Good Supplier In China High Purity Doramectin 117704-25-3 Doramectin Powder
117704-25-3 Good Supplier In China High Purity Doramectin 117704-25-3 Doramectin Powder
Doramectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. At 0.001 µg/ml, doramectin is fully effective at inhibiting growth in an H. contortus larval development assay.
Doramectin is a new generation of antiparasitic , compared with other commercially available ivermectin products, anti-parasite range of Doramectin is broader, with better effect, and Doramectin can prevent parasite reinfection for a longer valid time, It is the world's best, the most potential anti-parasitic drugs for development veterinary .
Doramectin as a pesticide can kill all the the internal and external parasites , and is also valid to nematodes, arthropods. At present, Chinese pig industry commonly used insecticide drugs include: parasite drugs: albendazole, levamisole, trichlorfon, Vietnam, hygromycin, ivermectin, avermectin. External parasite drugs: trichlorfon, amitraz, diazinon, permethrin drugs, avermectin, ivermectin.
Doramectin has a good effect on pig gastrointestinal nematodes , it is reported that pig is injected 0.3 mg/kg by intramuscular, dosing artificial and natural infection cases after 7 days , 14 days, 21 days, weight gains is significantly higher (swine P <0.0001); compared with the control group, percentage of getting rid of worms is 100%, and there are no side effects.
In Pig scabies mite treatment, from piglets to sows ,Doramectin has good results .After artificial infection scabies mites, according to the body weight ,administrated 0.3 mg/kg intramuscularly, four weeks after the test, the result of inflammation of the skin injury in pigs and worms Elimination of infected body, is very significant (P <0.05). Treatment for pregnant sows kidney worm, press the 0.3 mg/kg dose neck single injection, the 56 day and 57 day of testing, the detection rate of Urine eggs is 0, the percentage of getting rid of them is 100%, while the control group per milliliter of urine displays 3762 eggs. For lung worms, lice and other pigs parasites,it has the same effect.
Catalogue Number | D534500 |
Chemical Name | Doramectin |
Synonyms | 25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1A; 25-Cyclohexyl-avermectin B1; UK-67994; Dectomax; |
CAS Number | 117704-25-3 |
Molecular Formula | C??H??O?? |
Appearance | White to Off-White Solid |
Melting Point | 160-163ºC |
Molecular Weight | 899.11 |
Storage | -20°C Freezer |
Solubility | Chloroform (Sparingly), Methanol (Slightly) |
Category | Standards; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; |
Applications | Mutational biosynthetic antiparasitic antibiotic structurally related to the avermectins. |
CAS NO:525-82-6
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CAS NO:1150-90-9
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