Top quality Yohimbine HCL Reliable quality 65-19-0 65-19-0 Yohimbine

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Top quality Yohimbine HCL Reliable quality 65-19-0 Yohimbine 

Yohimbine HCL increases muscular tension, accelerates human body energy metabolism, increases energy supply.

Yohimbine has been shown in human studies to be effective in the treatment of male impotence. Yohimbine Hydrochloride has been shown to be effective in the treatment of orgasmic dysfunction in men. Yohimbine has also been used to treat hypoactive sexual desire disorder (reduced libido) in women.

Yohimbine hydrochloride is an α2-adrenergic receptor antagonist and increases the firing rate of the locus coeruleus with a resultant increase in sympathetic outflow (Redmond, 1987). Oral and intravenous yohimbine causes an increase in MHPG and blood pressure in healthy human subjects (Charney et al., 1982d; Goldberg et al., 1986). Depressed patients demonstrate an increased cortisol and blood pressure response to intravenous yohimbine compared with healthy subjects, while plasma MHPG is not significantly different between the two groups of subjects (Heninger et al., 1988). The effects of acute or chronic antidepressant treatments on the neuroendocrine or behavioural responses to yohimbine in depressed patients have not been studied.

Yohimbine hydrochloride is an α2-adrenoceptor antagonist (pK_i values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively). Yohimbine hydrochloride is an inhibitor of alpha2A-AR, alpha2B-AR and alpha2C-AR.