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6902-77-8 in stock lowest price Geniposide Supply Genipin
6902-77-8 in stock lowest price Geniposide Supply Genipin
Genipin is a compound isolated from gardenia fruits. Genipin is a water-soluble bifunctional crosslinking reagent with low cytotoxicity. Genipin is used as a good cross-linker for proteins, collagen, gelatin, and chitosan cross-linking. In addition, genipin can be used as a regulating agent for drug delivery, as an anti-inflammatory agent, and as the raw material for gardenia blue pigment preparation.
Genipin, a compound isolated from Gardenis jasminoides Ellis fruits, is a cell-permeable inhibitor of UCP2 activity. Genipin also exhibits anti-inflammatory and anti-angiogenic properties by inducing apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells.
Uncoupling protein 2 (UCP2) is a mitochondrial carrier protein that is expressed in pancreatic islets and has been shown to negatively regulate glucose-
Genipin is a compound isolated from Gardenis jasminoides Ellis fruits which acts as a cell permeable inhibitor of uncoupling protein 2 (UCP2). Genipin increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells. Genipin has been shown to induce apoptosis and is a protein cross-linking agent. Genipin, at 5 μM, increases glucose-stimulated insulin secretion in isolated pancreatic islets chronically exposed to high levels of glucose. Genipin also exhibits anti-inflammatory and anti-angiogenic properties by inducing apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells.
Catalogue number: | PA PHY 004152 |
Chemical name: | GENIPIN |
CAS Number: |
6902-77-8 |
Category: | NA |
Synonyms: |
(+)-Genipin; 1,4aα,5,7aα-Tetrahydro-1-hydroxy-7-(hydroxymethyl)-cyclopenta[c]pyran-4-carboxylic Acid; [1R-(1α,4aα,7aα)]-1,4a,5,7a-Tetrahydro-1-hydroxy-7-(hydroxymethyl)-cyclopenta[c]pyran-4-carboxylic Acid Methyl Ester |
Molecular form: | C11H14O5 |
Appearance: | NA |
Mol. Weight: | 226.23 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Genipin is an inhibitor of uncoupling protein 2 (UCP2). |
BTM: | NA |
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