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67-03-8 in stock Thiamine hydrochloride High quality Vitamin b1 on hot selling
67-03-8 in stock Thiamine hydrochloride High quality Vitamin b1 on hot selling
Thiamine hydrochloride plays an important role as a nutrient for carbohydrate metabolism and in nerve function. It finds application as a food-additive to add a brothy/meaty flavor to gravies or soups. It is involved in the preparation of 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazolium chloride. In addition, it finds use in amino acid synthesis in cultured cells, which is present in many classical and serum-free formulations.
Thiamine, also known as vitamin B1, is one of essential B vitamins that has many important functions in all tissues.1-3) Two types of water soluble thiamine salts, thiamine hydrochloride [T0181] and thiamine nitrate [T0182], are commonly used to products.4) Thiamine pyrophosphate (diphosphate) chloride [T0183] is the biologically active form of thiamine. In addition, thiamine hydrochloride is also used as an efficient catalyst for chemical reactions.7,8) For your reference, [A2633] is a key synthetic intermediate of thiamin.
Thiamine Hydrochloride is the hydrochloride salt form of thiamine (vitamin B1), a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Vitamin B1 helps prevent various health problems including heart damage.
Thiamine hydrochloride is used to prevent and treat thiamine deficiency states, which may occur as a result of inadequate nutrition or intestinal malabsorption. It is also used for the treatment of Wernicke-Korsakoff syndrome, beriberi and thiamine deficiency related to chronic alcoholism. Thiamine hydrochloride is used as a food additive to add brothy/meaty flavor to gravies or soups. It is used also as a food supplement and flavoring ingredient with a bitter taste.
Catalogue Number | T344185 |
Chemical Name | Thiamine Hydrochloride |
Synonyms | 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-chloridethiazolium Hydrochloride; Aneurine Hydrochloride; Apate Drops; Beatine; Bedome; Begiolan; Benerva; Eskapen; Eskaphen; Thiamin Dichloride; Vinothiam; Vitamin B1 Hydrochloride; Vitaneuron; |
CAS Number | 67-03-8 |
Alternate CAS # | 59-43-8-free base |
Molecular Formula | C??H??Cl?N?OS |
Appearance | White to Off-White Solid |
Melting Point | >224°C (dec.) |
Molecular Weight | 337.27 |
Storage | Refrigerator |
Solubility | DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated) |
Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Thiamine is a essential nutrient required for carbohydrate metabolism; also involved in nerve function. Biosynthesized by microorganisms and plants. Dietary sources include whole grains, meat products, vegetables, milk, legumes and fruit. Also present in rice husks and yeast. Converted in vivo to Thiamine diphosphate, a coenzyme in the decarboxylation of α-keto acids. Chronic deficiency may lead to neurological impairment, bariberi, Wernicke-Korsakoff syndrome. |
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