K252a

Min.Order / FOB Price:Get Latest Price

0 Metric Ton	Negotiable

0 Metric Ton

Negotiable

Min.Order :0 Metric Ton
Purity: 90%+
Payment Terms : T/T

Keywords

99533-80-9 K252a K252a, in stock

Quick Details

Appearance:Off-white to light yellow (Solid)
Application:Protein and CAM kinases inhibitor;Antitumor
PackAge:As per request
ProductionCapacity:|Metric Ton|Day
Storage:Store in a tight container at -20℃.
Transportation:by air or by sea

Superiority:

Product in stock

Short lead time

Cost competitiveness

Details:

K-252a, a staurosporine analog isolated from Nocardiopsis sp. soil fungi, inhibits protein kinase, with IC₅₀ values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca²⁺/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC₅₀ of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene.