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99% Bufexamac API Bufexamac Powder Raw Powder Bufexamac
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Product Name: Bufexamac
Synonyms: parfenac;p-butoxyphenylacetohydroxamicacid;AURORA KA-853;BUFEXAMAC;LABOTEST-BB LT00134645;2-(4-BUTOXYPHENYL)-N-HYDROXYACETAMIDE;2-(4-butoxyphenyl)
acetohydroxamic acid;2-(p-butoxyphenyl)acetohydroxamic acid
CAS: 2438-72-4
MF: C12H17NO3
MW: 223.27
EINECS: 219-451-1
Product Categories: Chemistry;Miscellaneous;-;Lipid signaling;API;NORFEMAC
Mol File: 2438-72-4.mol
Bufexamac Structure
Bufexamac Chemical Properties
Melting point 153-155°
Boiling point 364.56°C (rough estimate)
density 1.1223 (rough estimate)
refractive index 1.5300 (estimate)
solubility Practically insoluble in water, soluble in dimethylformamide, slightly soluble in ethl actate and in methanol.
form neat
Merck 14,1474
CAS DataBase Reference 2438-72-4(CAS DataBase Reference)
Safety Information
WGK Germany 2
RTECS AK8280000
Toxicity LD50 orally in mice, rats: >8, >4 g/kg (Lambelin)
Bufexamac is a drug used as an anti-inflammatory agent on the skin, as well as rectally. Common brand names include Paraderm and Parfenac. It was withdrawn in Europe because of allergic reactions.
Ointments and lotions containing bufexamac are used for the treatment of subacute and chronic eczema of the skin, including atopic eczema, as well as sunburn and other minor burns,[citation needed] and itching.Suppositories containing bufexamac in combination with local anaesthetics are used against haemorrhoids.
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