CasNo.15687-27-1,15687-27-1 good producer 15687-27-1 Ibuprofen Hot Sale Ibuprofen,(15687-27-1) Suppliers

1 Metric Ton	FOB Price: USD 10.0000

Min.Order :1 Metric Ton
Purity: 99%
Payment Terms : T/T,,MoneyGram

Keywords

15687-27-1 good producer 15687-27-1 Ibuprofen Hot Sale Ibuprofen

Quick Details

Appearance:white crystal powder
Application:Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used for relief of symptoms of arthritis, fever, as an analgesic (pain reliever), especially where there is an inflammatory component, and dy
PackAge:25kg/drum
ProductionCapacity:100|Metric Ton|Year
Storage:stay in dry, cool and well-sealed
Transportation:by speical line.Fedex,UPS

Superiority:

15687-27-1 good producer 15687-27-1 Ibuprofen Hot Sale Ibuprofen

Ibuprofen belongs to a non-steroidal anti-inflammatory analgesic. It has excellent anti-inflammatory, analgesic and antipyretic effect with less adverse reactions. It has been widely used in the world, as the world's best-selling non-prescription drugs. It, together with aspirin and paracetamol are listed as the three key antipyretic analgesics products. In our country, it is mainly used in pain alleviation and anti-rheumatism, etc. It has much less applications in the treatment of cold and fever compared with paracetamol and aspirin. There are a dozens of pharmaceutical companies qualified for production of ibuprofen in China. But the bulk of the domestic market sales of ibuprofen have been occupied by Tianjin Sino-US Company.

A nonsteroidal anti-inflammatory drug (NSAID) that acts as a reversible and competitive inhibitor of cyclooxygenase 1 (COX-1) (IC₅₀ = 4.85 µM). Inhibits COX-2 at higher concentrations (IC₅₀ = 223 µM). Blocks aspirin inactivation of COX-1 (EC₅₀ antagonism of 200 µM aspirin = 290 nM). Shown to reduce the total Aβ secretion (Amyloid β_{40 and 42}) in human neuronal cells and offers neuroprotection against glutamate-, nitric oxide-, and superoxide-induced damage. Reported to activate peroxisome proliferator-activated receptors (PPAR) α and γ in both CV-1 and C3H10T1/2 cells (~100 µM-500 µM).

Details:

Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.

Catalogue Number	KIT2585
Chemical Name	rac Ibuprofen (1.0 mg/mL in Methanol)
Synonyms	2-(4-Isobutylphenyl)propionic Acid;
CAS Number	15687-27-1
Molecular Formula	C??H??O?
Appearance	Colourless Solution
Melting Point	N/A
Molecular Weight	206.28
Storage	-20°C Freezer
Solubility	Methanol
Category	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Solutions; Kits;
Applications	A selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen has has been shown to reduce Ebola infection in rodents (4).This compound is a contaminant of emerging concern (CECs).