Methotrexate

Min.Order / FOB Price:Get Latest Price

1 Gram	FOB Price: USD 66.0000

1 Gram

FOB Price: USD 66.0000

Min.Order :1 Gram
Purity: 99%
Payment Terms : T/T,Other

Keywords

Methotrexate 59-05-2 99%

Quick Details

Appearance:powder
Application:intermediate
PackAge:according to your need for packing
ProductionCapacity:1|Metric Ton|Day
Storage:dry
Transportation:sea,air,courier

Superiority:

Methotrexate Chemical Properties
Melting point    195°C
alpha    +17～+24°(D/20℃)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis)
Boiling point    561.26°C (rough estimate)
density    1.4080 (rough estimate)
refractive index    1.6910 (estimate)
Fp    11℃
storage temp.    Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility    H2O: insoluble
form    powder
pka   pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain)
Water Solubility    Insoluble. <0.1 g/100 mL at 19 ºC
Sensitive    Light Sensitive & Hygroscopic
Merck    14,5985
BRN    70669
Stability:   Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below.
InChIKey   FBOZXECLQNJBKD-ZDUSSCGKSA-N
CAS DataBase Reference   59-05-2(CAS DataBase Reference)
IARC   3 (Vol. 26, Sup 7) 1987
NIST Chemistry Reference   Methotrexate(59-05-2)
EPA Substance Registry System   Methotrexate (59-05-2)

Details:

Methotrexate Basic information
Treatment of cancer and rheumatoid arthritis History of discovery Immunosuppressants Pharmacological effects Pharmacokinetics Clinical application Dosage Adverse reactions and precautions Drug Interactions Chemical Properties Production method
Product Name:   Methotrexate
Synonyms:   METHOTREXATEFORINJECTION;sodium 4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]am ino]-5-hydroxy-5-oxo-pentanoate;METHOTREXATE(N-(4-(((2,4-DIAMINO-6-PTERIDINYL)METHYLAMINO)BENZOYL)-L-GLUTAMICACID);4-Amino-N10-methylfolic acid;Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)- (8CI);L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI);L-Methotrexate;Methotrexat-Ebewe
CAS:   59-05-2
MF:   C20H22N8O5
MW:   454.45
EINECS:   200-413-8
Mol File:   59-05-2.mol

Safety Information
Hazard Codes    T,F
Risk Statements    61-25-36/38-46-39/23/24/25-23/24/25-11
Safety Statements    53-26-36/37-45-36/37/39-36-16
RIDADR    UN 2811 6.1/PG 3
WGK Germany    3
RTECS    MA1225000
F    3-8-10
TSCA    Yes
HazardClass    6.1(b)
PackingGroup    III
HS Code    29335995
Hazardous Substances Data   59-05-2(Hazardous Substances Data)
Toxicity   LD50 oral in rat: 135mg/kg