supplier 120511-73-1 good producer 120511-73-1 Hot Sale Anastrozole

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1 Kilogram	FOB Price: USD 1.0000

1 Kilogram

FOB Price: USD 1.0000

Min.Order :1 Kilogram
Purity: 99%min
Payment Terms : T/T,

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supplier 120511-73-1 good producer 120511-73-1 Hot Sale Anastrozole

Quick Details

Appearance:White powder
Application:anastrozole has proven to be very effective in breast cancer treatment, even more so than traditional novadex (tamoxifen citrate), and is a favorite anti-estrogen among many anabolic steroid users. co
PackAge:1kg/pack,10kg/pack(Aluminum Foil Bag)
ProductionCapacity:1000|Kilogram|Year
Storage:Store in dry,ventilated place under normal temperature
Transportation:By FEDEX,DHL

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supplier 120511-73-1 good producer 120511-73-1 Hot Sale Anastrozole

Anastrozole, chemically known as 2,2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropiononitrile) a derivative of benzotriazole with the CAS registry number 120511-73-1, is a non-steroidal, third-generation achiral triazole derivative marketed as ARIMIDEX® by AstraZeneca Pharmaceuticals LP1. It is one of the third-generation aromatase inhibitor which is a highly competitive and selective inhibitor of aromatase, thus blocking the conversion of testosterone into estradiol and androstenedione into estrone. Inhibition of the aromatase enzyme occurs particularly through competitive binding of aromatase to the hemegroup of cytochrome P450, decreasing estrogen biosynthesis in the peripheral tissues of the body and in the breast.

Anastrozole is a potent and highly selective aromatase (CYP19) inhibitor (IC₅₀ = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo. Orally active.

Details:

Catalogue Number	A637425
Chemical Name	Anastrozole
Synonyms	α1,α1,α3,α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile; 2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile; Anastrazole; Anastrol; Arimidex; ICI-D 1033; ZD 1033
CAS Number	120511-73-1
Molecular Formula	C??H??N?
Appearance	White to Off-White Solid
Melting Point	81-82°C
Molecular Weight	293.37
Storage	-20°C Freezer
Solubility	Chloroform (Slightly), Methanol (Slightly)
Category	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	An aromatase inhibitor. Used as an antineoplastic.