Trioxsalen Trioxsalen manufacturer/supplier 3902-71-4
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Hangzhou Jinlan Pharm-Drugs Technology Co., Limited is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l Airport, the transportation and production environment are excellent.
We have established well market channels both domestically and overseas. Now JINLAN PHARMA is authorized by some Chinese chemical factories as universal agency and international area agency. Our products are exported to more than 100 countries and enjoy a well reputation, including Europe, USA, South America, India, south-east Asia and so on. Such as Canada, Germany, Spain, Australia, Russia, UAE, Estonia, Indonesia, Egypt, Pakistan and so on. Our machines with Excellent quality, Competitive price, Good after-service, are highly welcomed by our customers. We are pleased to know you and hope to be good friend and cooperator with you for our products. I am sure you will be satisfied with us.
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Trioxsalen (trimethylpsoralen, Trioxysalen or Trisoralen) is a furanocoumarin and a psoralen derivative. It is obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death unless repaired by cellular mechanisms. In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage. The compound is also being explored for development of antisense oligonucleotides that can be cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair.
Chemical Name |
trioxsalen |
Synonyms |
4,2',8-trimethylpsoralen;4,5',8-Trimethylpsoralen;Trisoralen;2,5,9-trimethylfuro[3,2-g]chromen-7-one;Trioxysalenum;Expand |
CAS No. |
3902-71-4 |
Molecular Formula |
C14H12O3 |
Molecular Weight |
228.24300 |
PSA |
43.35000 |
LogP |
3.46440 |
UNII |
Y6UY8OV51T |
Appearance & Physical State |
Crystalline Powder |
Density |
1.236 g/cm3 |
Boiling Point |
389ºC at 760 mmHg |
Melting Point |
229-231ºC(lit.) |
Flash Point |
189.1ºC |
Refractive Index |
1.613 |
Storage Condition |
2-8ºC |
Safety Statements |
S26; S36/37/39; S45 |
HS Code |
2932999099 |
RIDADR |
UN 1759 8 |
Risk Statements |
R34; R40 |
Hazard Codes |
C |
Hazard Declaration |
H314; H351 |
Caution Statement |
P280; P305 + P351 + P338; P310 |
Symbol |
GHS05, GHS08 |
Signal Word |
Danger |
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