Tylvalosin 63409-12-1 Tylvalosin
High quality
Short lead time
Cost competitiveness
Tylvalosin is a macrolide antibiotic. It is active against S. aureus, E. coli, and P. multocida (MICs = 2, 128, and 128 µg/ml, respectively). Tylvalosin (5 and 10 µg/ml) reduces LPS-induced production of pro-inflammatory cytokines, prostaglandin E2 (PGE2), and nitric oxide in RAW 264.7 cells. It reduces the severity of lung lesions in pigs infected with M. hyopneumoniae and P. multocida when administered at a dose of 10 mg/kg per day in the drinking water. Formulations containing tylvalosin have been used in the treatment and metaphylaxis of enzootic pneumonia caused by M. hyopneumoniae in pigs.
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