Gabapentin in bulk supply 60142-96-3 global trade Hot Sale 60142-96-3

Gabapentin in bulk supply 60142-96-3 global trade Hot Sale 60142-96-3

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price: USD 10.0000

1 Kilogram

FOB Price: USD 10.0000

Min.Order :1 Kilogram
Purity: >99%
Payment Terms : T/T,,MoneyGram

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Gabapentin in bulk supply 60142-96-3 global trade Hot Sale 60142-96-3

Quick Details

Appearance:White solid
Application:pharmaceutical intermediates
PackAge:1kg/Aluminum foil package, 25Kg/Drum
ProductionCapacity:|Metric Ton|Day
Storage:Normal temperature
Transportation:FEDEX,DHL,EMS,Special line guarantee delivery

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Gabapentin in bulk supply 60142-96-3 global trade Hot Sale 60142-96-3

Although gabapentin has no approved indications in psychiatry, it has shown efficacy in the treatment of anxiety disorders, especially social phobia. Other offlabel uses include other anxiety disorders (panic disorder, post- traumatic stress disorder), alcohol dependence and withdrawal, behavioural and psychological symptoms of dementia, and aggression. Gabapentin has also been proposed to be useful in the maintenance treatment of bipolar disorder as adjunctive therapy.

A water soluble GABA analog originally developed to treat epilepsy and neuropathic pain but is not believed to act on the same brain receptors. Gabapentin interacts with voltage-gated calcium channels in cortical neurons. It binds to the α2δ subunit (1 and 2) and has been found to reduce calcium currents after chronic but not acute application via an effect on trafficking of voltage-dependent calcium channels in the central nervous system.

Anticonvulsant with several possible mechanisms of action. Increases GABA in the brain and binds to a novel site associated with voltage-sensitive Ca²⁺ channels. Prevents neuronal death and is antinociceptive and anxiolytic.

Details:

Catalogue Number	G117250
Chemical Name	Gabapentin
Synonyms	1-(Aminomethyl)cyclohexaneacetic Acid, Neurontin, GOE-3450
CAS Number	60142-96-3
Molecular Formula	C?H??NO?
Appearance	White to Off-White Solid
Melting Point	161-163°C
Molecular Weight	171.24
Storage	Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility	Methanol (Slightly), Water (Slightly)
Stability	Hygroscopic
Category	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	Gabapentin is an Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.

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