best price Factory Supply 30123-17-2 Tianeptine sodium

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best price Factory Supply 30123-17-2 Tianeptine sodium

Sodium nipputin is a tricyclic antidepressant whose antidepressant mechanism is different from that of traditional tricyclic antidepressants, which can increase the reuptake of synaptic gap 5-HT, which may have the effect of improving the conduction of 5-HT neurons. There is no affinity for choline or adrenaline receptors. Antidepressant efficacy is similar to tricyclic, but tolerability is better than tricyclic.Used to treat mild, moderate or severe depression, neurogenic and reactive depression, anxiety depression of the body, especially gastrointestinal discomfort, and alcohol dependence on anxiety depression in patients during withdrawal. The recommended dose is 12.5 mg, tid, orally before the morning, middle and evening main meal. People with chronic alcoholism, whether or not they have cirrhosis, do not need to adjust the dose. For patients over 70 years of age and with renal insanity, the dose is limited to 2 tablets per day.

In animal experiments, the spontaneous activity of cone cells in hippocampus can be increased and the recovery of its function can be accelerated after inhibition. It can increase the reabsorption of neurons in the cerebral cortex and hippocoma to serotonin. Sodium neputin absorbs rapidly and completely in the digestive tract. The distribution is rapid, with PPBs as high as 94%. In the liver through β-oxidation and N-methyl action metabolism completely, the elimination of end-of-life T1/2 short, for 2.5h, very small amount of primary drugs (8%) excreted from the kidneys, mainly its metabolites excreted from urine. Renal insanity patients clear T1/2 extension 1h.