120511-73-1 in stock Hot Sale 120511-73-1 120511-73-1 Anastrozole
in stock Hot Sale 120511-73-1 Anastrozole
Name : Anastrozole
Product name: Anastrozole
Chemical name: α,α,α',α'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3- benzenediacetonitrile
Molecular formula: C17H19N5
Molecular weight: 293.37
CAS NO.: 120511-73-11
Appearance: white crystalline powder
Synonyms Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile
Molecular Formula C17H19N5
Molecular Weight 293.37
CAS Registry Number 120511-73-1
Properties
Melting point 81-82 ºC
For the treatment of breast cancer.
Anastrozole is a potent and selective triazole aromatase inhibitor. It can inhibit the aromatase on which cytochrome P-450 depends to block the biosynthesis of estrogen, and estrogen stimulates the growth of breast cancer cells The main factor. The 50% inhibitory concentration (IC50) value of this product on human placental aromatase is 15nmol/L. Letrozole is suitable for postmenopausal advanced breast cancer, and is mostly used for second-line treatment after the failure of anti-estrogen therapy.
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