factory supply GMP,WC Sacubitril + Valsartan

factory supply GMP,WC Sacubitril + Valsartan

Min.Order / FOB Price:Get Latest Price

1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: USP/EP/BP
Payment Terms : L/C,T/T,Other

Keywords

Sacubitril + Valsartan LCZ696 936623-90-4

Quick Details

Appearance:White crystallization
Application:Cardiovascular APIs,Sartan antihypertensive drugs
PackAge:25kg/drum
ProductionCapacity:10|Metric Ton|Day
Storage:room temperature
Transportation:AIR SEA TRAIN

Superiority:

We are very compeitive on Sacubitril + Valsartan.Our mfr is GMP certified for this item with WC document.

LCZ696 , a first-in-class inhibitor of dualacting angiotensin-2 type-I receptor and neprilysin inhibitors, was developed as a molecule composed of molecular moieties of valsartan and neprilysin inhibitor prodrug AHU377 in a 1:1 ratio. Several phase 2 randomised clinical trials have been done or are underway in patients with hypertension. In a proof-of-concept randomised trial, LCZ696 was compared with valsartan in 1328 patients with mild-to-moderate hypertension, and provided fully additive reduction of blood pressure. No cases of angio-oedema were reported in the 8 week treatment period. This tolerance should be confirmed, particularly in black patients, for whom omapatrilat resulted in a higher occurrence of angio-oedema than in white patients. Indeed, in the proof-of-concept trial only about 8% of patients were black.

Details:

Product Name:	LCZ696
Synonyms:	Sacubitril mixture with Valsartan
CAS:	936623-90-4
MF:	C48H58N6O8
MW:	847.03
Product Categories:	Cardiovascular Series;Inhibitors;API