Polyinosinic acid 30918-54-8 PolyI

Details:

【Product name】 Polyinosinic acid
【Synonyms】PolyI; Poly(rI); Poly(IMP); 
                     Polyinosinic acid; 
                     Poly(5-inosinicacid);
                     Polyinosinic Acid 90%; 
                     polyinosinicacidpot.salt; 
                     5'-Inosinic acid polymers; 
                     Polyinosinic acid (Poly I)
【CAS NO.】30918-54-8
【Content】≥90%
【Mol. Formula】(C10H13N4O8P) n  
【Mol. Weight】348.21
【Appearance】Off-white Powder
【Standard】Medicine grade, Tech. grade
【Packing】500g/Bottle
【Storage】Keep tightly closed and store below 20℃

Polyinosinic-polycytidylic acid (polyi:c) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor (TLR) 3 and retinoic acid inducible gene I (RIG-I)-like receptors (RLRs), including RIG-I and melanoma differentiation-associated gene 5 (MDA5). The effect of polyi:c on tumor immunotherapy has been well explored for several decades. The accumulated evidence suggests that polyi:c could be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Recent studies have also shown that activation of TLR3 and RLR signaling by polyi:c can directly trigger apoptosis in some cancer cells. This review focuses on polyi:c-induced signaling pathways and the applications of polyi:c in cancer treatment.

Shanghai Soyoung Biotechnology Inc. a faithful and professional supplier and exporter of healthcare raw materials for pharmacy, nutrition and food industries for years with own laboratory and GMP standard factories.

Shanghai Soyoung has R&D Center and Testing Center, and has international advanced facilities of HPLC, GC, AAS, UV, TLC, LC-MS and IR equipments. 

Shanghai Soyoung has nearly 20 years production experience, it is producing in GMP workshop, each batch pass strict testing before shipment. Strict quality control is performed in every procedure from material sourcing, processing and testing to packing.

Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many years, with own laboratories and GMP standard factories.

1. 12 years specialized in health products field.
2. GMP/ISO certificated factories and stable supply chain.
3. Quality first, strictly control before shipments.
4. Custom synthesis by more than 20 professional chemists.
5. Small order,free sample and one step service available.
6. Rapid delivery, 1-6 business days from China warehouse.
7. Support 7 days refund money in case delay shipment.
8. Assessment conducted by Bureau Veritas at 2018.