5-Bromoindole-2-carboxylic acid 7254-19-5 98% purity
Product Name: 5-Bromoindole-2-carboxylic acid
Synonyms: 5-BROMO-1H-INDOLE-2-CARBOXYLIC ACID;5-BROMO-2-INDOLECARBOXYLIC ACID;5-BROMOINDOLE-2-CARBOXYLIC ACID;AKOS JY2082545;1H-INDOLE-2-CARBOXYLIC ACID, 5-BROMO-;5-bromoindole-2-carboxylicacid5-Bromoindole-2-carboxylicacid;5-Bromoindole-2-carboxylic acid ,98%;5-BroMo-1H-indol-2-carboxylic acid
CAS: 7254-19-5
MF: C9H6BrNO2
MW: 240.05
EINECS:
Mol File: 7254-19-5.mol
Melting point 287-288
Boiling point 470.9±25.0 °C(Predicted)
density 1.838±0.06 g/cm3(Predicted)
storage temp. -20°C
pka 4.25±0.30(Predicted)
form Solid
CAS DataBase Reference 7254-19-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39-36/37/39
WGK Germany 3
Hazard Note Irritant
HazardClass IRRITANT
HS Code 29339980
MSDS Information
Provider Language
SigmaAldrich English
5-Bromoindole-2-carboxylic acid Usage And Synthesis
Uses 5-Bromoindole-2-carboxylic acid,Reactant involved in studies of biologically active molecules including:Discovery of indole inhibitors of MMP-13 for treatment of arthritic diseases1;Synthesis of indolyl ethanones as indoleamine 2,3-dioxygenase inhibitors2 ;cis-Diaminocyclohexane derivatives prepared for use as factor Xa inhibitors3 ;Synthesis of tubulin polymerization inhibitors and cancer cell growth inhibitors4 ;Preparation of dual PPARγ/δ agonists5;Synthesis of chemical probes to examine the role of hFPRL1 receptor .
5-Bromoindole-2-carboxylic acid Preparation Products And Raw materials
Raw materials Ethanol-->Polyphosphoric acid-->Ethyl pyruvate-->Lithium hydroxide-->4-BROMOPHENYLHYDRAZINE HYDROCHLORIDE
Preparation Products 2-(Ethoxycarbonyl)-5-bromo-indole-->5-Bromoindole-2-carboxylic acid methyl ester
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