(S)-1,2,4-Butanetriol

Details:

alpha     -30 º (c=1, MeOH)
Boiling point     150 °C0.04 mm Hg(lit.)
density     1.19 g/mL at 25 °C(lit.)
refractive index     n20/D 1.475(lit.)
Fp     >110°C
storage temp.     Inert atmosphere,Room Temperature
pka    14.02±0.20(Predicted)
Specific Gravity    1.190
optical activity    [α]19/D 28±2, c = 1 in methanol
Water Solubility     soluble
Sensitive     Hygroscopic
BRN     1719408
CAS DataBase Reference    42890-76-6(CAS DataBase Reference)
Safety Information
Hazard Codes     F,Xn
Risk Statements     36/37/38-41-20/21/22-11
Safety Statements     23-24/25-39-26-16-36/37-28-33-29-9
RIDADR     UN 3316 9/PG 2
WGK Germany     3
F     3-10-21
MSDS Information
Provider    Language
ACROS    English
SigmaAldrich    English
ALFA    English
(S)-1,2,4-Butanetriol Usage And Synthesis
Description    
(S)-(-)-1,2,4-Butanetriol can be prepared via reduction of (S)-malic acid in the presence of borane-dimethyl sulfide. (S)-(-)-1,2,4-Butanetriol may be used as a starting material in the enantioselective total syntheses of (+)-azimine and (+)-carpaine. It can also be used to prepare the organic building blocks (+)-3,4-epoxy-1-butanol, (2S,4S)-4-(hydroxymethyl)-2-ferrocenyl-1,3-dioxan, (S)-1,2,4-triacetoxybutane via acetylation with acetic anhydride, and (S)-1,2,4-tris-(3,5-dinitrobenzoy1oxy)butane via esterification with 3,5-dinitrobenzoyl chloride, and so on.

Chemical Properties    clear colorless viscous liquid
(S)-1,2,4-Butanetriol Preparation Products And Raw materials
Raw materials    2-Butanol, 1,4-bis(phenylmethoxy)-, (2S)--->Dimethyl malate