Ethyl 4,6-dichloronicotinate 40296-46-6 98% purity
Product Name: Ethyl 4,6-dichloronicotinate
Synonyms: 4,6-Dichloronicotinic acid ethyl ester ,97%;ethyl 4,6-dichloronicotinate (en);Ethyl 4,6-dichloronicotinate ,97%;ethyl 4,6-dichloropyridine-3-carboxylate;3-Pyridinecarboxylicacid,4,6-dichloro-,ethylester;4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER;4,6-DICHLORONICOTINIC ACID ETHYL ESTER;ETHYL 4,6-DICHLORONICOTINATE
CAS: 40296-46-6
MF: C8H7Cl2NO2
MW: 220.05
EINECS:
Mol File: 40296-46-6.mol
Melting point 32-34°
Boiling point 85°C/0.01mmHg(lit.)
density 1.367±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol.
pka -1.24±0.10(Predicted)
form Liquid
color Yellow
InChIKey AAUBVINEXCCXOK-UHFFFAOYSA-N
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36
HazardClass IRRITANT
HS Code 29339900
MSDS Information
Ethyl 4,6-dichloronicotinate Usage And Synthesis
Uses Ethyl 4,6-Dichloronicotinate acts as a reactant in the preparation of (acylamino)aminonaphthyridinones as novobiocin analogs and Hsp90 inhibitors, their antitumor activities in human breast cancer cell lines, and the effects on aptoptosis and cell cycle advancement of selected compounds.
Chemical Properties White solid
Ethyl 4,6-dichloronicotinate Preparation Products And Raw materials
Raw materials Ethanol-->Sodium hydroxide-->Hydrochloric acid-->Phosphorus oxychloride-->Acetic anhydride-->Ammonium hydroxide-->Triethyl orthoformate-->Diethyl 1,3-acetonedicarboxylate
Preparation Products 4,6-DICHLORO-3-PYRIDINEMETHANOL-->6-Chloro-1H-pyrazolo[4,3-c]pyridine
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