- Min.Order :1 Kilogram
- Purity: USP/EP/BP
- Payment Terms : L/C,T/T,Other
Keywords
Ritonavir Anti-AIDS 155213-67-5
Quick Details
- Appearance:White crystallization
- Application:Anti- Virus response
- PackAge:1kg/tin
- ProductionCapacity:1|Metric Ton|Day
- Storage:
- Transportation:AIR SEA TRAIN
Superiority:
We are very compeitive on Ritonavir.Our mfr is GMP certified for this item with DMF document.
| Product Name: | Ritonavir |
| CAS: | 155213-67-5 |
| MF: | C37H48N6O5S2 |
| MW: | 720.94 |
| EINECS: | 605-001-5 |
| Product Categories: | Inhibitor;peptides;NORVIR;API;Ritonavir;Pharmaceutical;Anti-viral Compounds;Anti-virals;Inhibitors;Intermediates & Fine Chemicals;Non-nucleoside Reverse Transcriptase;Pharmaceuticals;Steroids;HIV/AIDS/Related Products;Anti-AIDS;Sulphur Derivatives;Active Pharmaceutical Ingredients |
| Mol File: | 155213-67-5.mol |
Details:
| escription | Norvir was launched in Germany, the UK and US for treatment of advanced HIV in combination with antiretroviral nucleoside analogs in a record 72 days by the FDA. It is an inhibitor of HIV aspartic protease which is critical in the processing of a propeptide into the gag, gag-pol gene products and the protease itself. This inhibition results in the release of non-infectous immature virus particles. It is greater than 500-fold more selective for viral aspartic protease than the human version, has good oral bioavailability and may increase the bioavailability of other protease inhibitors. Ritonavir was able to increase the CD4 and CD8 lymphocyte count as well as reduce viral RNA. It is more potent than saqunavir and comparible in potency to zidovudine and lamivudine. |
| Chemical Properties | White or almost white powder. |
| Originator | Abbott (USA) |
| Uses | Protease inhibitor; antiviral (HIV). |
| Uses | Ritonivir is an HIV protease inhibitor (EC50 = 25 nM) that also inhibits CYP3A4, the primary cytochrome P450 isoform that metabolizes protease inhibitors. Through CYP3A4 inhibition, low doses of ritonivir can reduce the metabolism of concomitantly administered protease inhibitiors, enhancing their bioavailability and efficacy.[Cayman Chemical] |
| Uses | A selective HIV protease inhibitor |
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