1,4,8,11-TETRAAZACYCLOTETRADECANE 295-37-4 99% purity
Product Name: 1,4,8,11-TETRAAZACYCLOTETRADECANE
Synonyms: 1,4,8-Tris(trifluoroacetyl)-1,4,8,11-tetraazacyclotetradecane;1,4,8-Tris(trifluoroacetyl)cyclaM;cyclaM, Methanol adduct;1,4,8,11-Tetraazacyclotetradecane 98% (GC);jm1498;CYCLAM;Cyclam, 98+%;1,4,8,11-TETRAAZACYCLOTETRADECANE
CAS: 295-37-4
MF: C10H24N4
MW: 200.32
EINECS: 206-039-1
Mol File: 295-37-4.mol
Melting point 184-186 °C (lit.)
Boiling point 328.07°C (rough estimate)
density 1.0203 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 10.90±0.20(Predicted)
form Fluffy Needle-Like Crystalline Powder
color White
Water Solubility Soluble in water.
Sensitive Air Sensitive
BRN 111811
InChIKey MDAXKAUIABOHTD-UHFFFAOYSA-N
CAS DataBase Reference 295-37-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS XA5254800
F 3-9-34
HS Code 29339900
Toxicity LD50 intraperitoneal in mouse: 371mg/kg
MSDS Information
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1,4,8,11-TETRAAZACYCLOTETRADECANE Usage And Synthesis
Chemical Properties white fluffy needle-like crystalline powder
Uses Reagent used in the preparation of Plerixafor derivatives.
Uses 1,4,8,11-Tetraazacyclotetradecane is macrocyclic ligand that is used as an antioxidant in rubber and has been shown to suppress oxidation catalyzed by some metal ions.
Purification Methods Purify cyclam by recrystallisation from dioxane (white needles), and it sublimes above 120o. It has been distilled, b 132-140o/4-8mm. It forms complexes with metals and gives a sparingly soluble nitrate salt, m 205o(dec), which crystallises from H2O and is dried at 150o. [UV: Bosnich et al. Inorg Chem 4 1102 1963, van Alphen Recl Trav Chim Pays-Bas 56 343 1937, Beilstein 26 III/IV 1647.]
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