Pyroxamide

Min.Order / FOB Price:Get Latest Price

1 Gram	Negotiable

1 Gram

Negotiable

Min.Order :1 Gram
Purity: 98% purity
Payment Terms : T/T,Other

Keywords

Pyroxamide 382180-17-8 98% purity

Quick Details

Appearance:powder
Application:intermediate
PackAge:accroding to the need
ProductionCapacity:100|Kilogram|Day
Storage:Sealed in dry,Room Temperature
Transportation:air，sea and courier

Superiority:

Product Name:   Pyroxamide
Synonyms:   382180-17-8; NSC-696085; N-HYDROXY-N'-3-PYRIDINYLOCTANEDIAMIDE; N-HYDROXY-N'-(PYRIDIN-3-YL)OCTANEDIAMIDE; NSC696085; NSC 696085;n-hydroxy-n'-(pyridin-3-yl)octanediamide;NSC 696085;Pyroxamide ;2-[1-carbaMoyl-N-(2H-pyran-2-yl)forMaMido]-N-hydroxy-N'-(pyridin-3-yl)octanediaMide;PyroxaMide (NSC 696085);N1-Hydroxy-N8-3-pyridinyl-octanediamide;N1-Hydroxy-N8-(pyridin-3-yl)octanediamide
CAS:   382180-17-8
MF:   C13H19N3O3
MW:   265.31
EINECS:
Product Categories:
Mol File:   382180-17-8.mol

Details:

storage temp.    -20°C
solubility    DMSO: soluble10mg/mL (clear solution)
form    powder
color    white to beige
Safety Information
Hazard Codes    Xn
Risk Statements    22
WGK Germany    3
MSDS Information
Pyroxamide Usage And Synthesis
Uses   Pyroamide is a histone decetylase inhibitor (HDCi), a novel class of anti-neoplastic agent that acts by enhancing acetylation of histones, promoting uncoiling of chromatin and activation of genes imp licated in the regulation of cell survival such as poliferation, differentiation and apoptosis. Pyroamide is known to potently inhibits affinity purified HDAC1. Also inhibits the growth of tumor cells in vitro and in vivo. Induces p21/WAF1 expression in tumor cells.
Uses   Pyroxamide is an inhibitor of histone deacetylases (HDACs), including HDAC1 (IC50 = 0.1-0.2 μM). It induces growth suppression and cell death of certain types of cancer cells in culture.

View All