7,8-Dihydroxyflavon...

7,8-Dihydroxyflavone    manufacturer/supplier    manufacturer/supplier

7,8-Dihydroxyflavone manufacturer/supplier manufacturer/supplier

Min.Order / FOB Price:Get Latest Price

1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram

Keywords

7,8-Dihydroxyflavone 7,8-Dihydroxyflavone manufacturer/supplier 38183-03-8

Quick Details

  • Appearance:white or off-white powder
  • Application:7,8-Dihydroxyflavone CAS:38183-03-8 is used as API medicine
  • PackAge:aluminum oil bag
  • ProductionCapacity:1000|Metric Ton|Month
  • Storage:0~20℃
  • Transportation:by express,by sea, by air

Superiority:

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO business service because of capacity limit, product cost limit or developing limit, plz feel free to contact us. 

Besides, we could discuss the possible FDF distribution business. Hope to get the chance to discuss deeply.

 

 

 

 

Details:

Hangzhou Jinlan Pharm-Drugs Technology Co., Limited  is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l Airport, the transportation and production environment are excellent.

We have established well market channels both domestically and overseas. Now JINLAN PHARMA is authorized by some Chinese chemical factories as universal agency and international area agency. Our products are exported to more than 100 countries and enjoy a well reputation, including Europe, USA, South America, India, south-east Asia and so on. Such as Canada, Germany, Spain, Australia, Russia, UAE, Estonia, Indonesia, Egypt, Pakistan and so on. Our machines with Excellent quality, Competitive price, Good after-service, are highly welcomed by our customers. We are pleased to know you and hope to be good friend and cooperator with you for our products. I am sure you will be satisfied with us.

Based on the philosophy of “Human-orient, Technical first, Quality product and High efficiency, Fact and Innovation”, JINLAN PHARMA highly welcome friends from all over the world to cooperate and get co-development. 

Basic Info

Chemical Name

3-Chloro-4-MetDescription

7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF). 7,8-DHF is both orally-bioavailable and able to penetrate the blood-brain-barrier.
7,8-DHF has demonstrated remarkable therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, Alzheimer's disease, cognitive deficits in schizophrenia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome. 7,8-DHF also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents. In addition, 7,8-DHF possesses powerful antioxidant activity independent of its actions on the TrkB receptor, and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity. It was also found to block methamphetamine-induced dopaminergic neurotoxicity, an effect which, in contrast to the preceding, was found to be TrkB-dependent.

Basic Info

Chemical Name

7,8-DIHYDROXYFLAVONE

Synonyms

7,8-dihydroxy-2-phenylchromen-4-one;7,8-Dihydroxyflavone Hydrate;7,8-Dihydroxy-2-phenyl-4H-chromen-4-one;7,8-Dihydroxyflavone;

CAS No.

38183-03-8

Molecular Formula

C15H10O4

Molecular Weight

254.23700

PSA

70.67000

LogP

2.87120

Numbering system

MDL number

MFCD00006836

Properties

Density

1.443g/cm3

Boiling Point

494.4ºC at 760 mmHg

Melting Point

243-246ºC

Flash Point

193.5ºC

Refractive Index

1.698

Safety Info

RTECS

DJ3004000

Safety Statements

24/25

HS Code

2914400090

Hazard Declaration

H302

Signal Word

Warning

Symbol

GHS07

hoxybenzylamine Hydrochloride

Synonyms

(3-Chloro-4-methoxyphenyl)methanamine hydrochloride;(3-chloro-4-methoxyphenyl)methanaminehydrochloride;3-Chloro-4-methoxybenzylamine Hydrochloride;

CAS No.

41965-95-1

Molecular Formula

C8H11Cl2NO

Molecular Weight

208.08500

PSA

35.25000

LogP

3.30960

Numbering system

MDL number

MFCD01211460

Properties

Appearance & Physical State

WHITE TO YELLOW POWDER, CRYSTALS OR CRYSTALLINE POWDER AND/OR CHUNKS

Boiling Point

263.5ºC at 760 mmHg

Melting Point

250-255ºC(lit.)

Flash Point

113.2ºC

Safety Info

Safety Statements

26-36/37-45

HS Code

2922299090

WGK Germany

3

RIDADR

UN 2811 6

Risk Statements

R25

Hazard Codes

T

 

 

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