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577778-58-6 Topiroxostat High purity Topiroxostat
Description
Topiroxostat is a selective xanthine oxidoreductase inhibitor for the treatment of gout and hyperuricemia.
UsesTopiroxostat, a selective xanthine oxidoreductase inhibitor, is used in Japan for the treatment of hyperuricemic patients with or without gout. In terms of the effectiveness of topiroxostat in lowering serum urate levels, the dose-response relationship has been evaluated; however, it remains to be verified.Clinical UseTopiroxostat, a novel XO inhibitor, ameliorated proteinuria in association with podocyte injury markers such as decrease in WT-1 and podocin expressions and foot process effacement on electron microscope.
Product Name:Topiroxostat
CAS:577778-58-6
MF:C13H8N6
MW:248.24282
EINECS:1592732-453-0
Mol File:577778-58-6.mol
Boiling point:594.7±60.0 °C(Predicted)
Density 1.45±0.1 g/cm3(Predicted)
Items | Specification |
Result |
Purity(HPLC) | ≥99% | 99.75% |
Apperance | Off-white to light yellow powder | Off-white powder |
Loss on drying | ≤0.5% | 0.34% |
Residue on ignition | ≤0.5% | 0.1% |
Largest single purity | ≤0.5% | 0.08% |
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