CasNo.147098-20-2,Rosuvastatin Calcium CAS 147098-20-2,(147098-20-2) Suppliers

1 Gram	FOB Price:USD 95.0000 -100.0000

Min.Order :1 Gram
Purity: 99%
Payment Terms : T/T,

Keywords

Rosuvastatin Calcium CAS 147098-20-2 147098-20-2

Quick Details

Appearance:white powder
Application:Animal Pharmaceuticals
PackAge:carton boc
ProductionCapacity:1000000|Kilogram|Month
Storage:cool and dry
Transportation:ship,fly

Superiority:

Hebei Mojin Biotechnology Co., Ltd,Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

Adenosine triphosphate can be used in the disease caused by tissue injury and activity reduction of ecto enzyme , including heart failure, carditis, miocardial infarction, cerebral arteriosclersis, coronary sclerosis, progressive muscular atrophy , cerebral hemorrhage , chronic hepatitis, cirrhosis of liver and hearing handicap, etc.

Details:

Product Detailed

Rosuvastatin, one of the two new statins launched for the treatment of hypercholesterolemia, has high hepato-selectivity and more potent inhibitory effect on HMG-CoA reductase than the previously marketed statins. In rat hepatocytes, it inhibits cholesterol biosynthesis with an IC50 of 1.12 nM, which is ~100-fold higher potency than pravastatin. Rosuvastatin is synthesized in a 12-step sequence, entailing the construction of a pyrimidinyl aldehyde intermediate in eight steps and subsequent introduction of the dihydroxyheptenoate side chain via Wittig reaction with a bketophosphorane reagent and stereoselective carbonyl reduction of the resultant enone.

FUNCTION

1. A selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
2. Rosuvastatin can reduce elevated LDL cholesterol, total cholesterol, triglycerides and ApoB, increased HDL- cholesterol.
3. Rosuvastatin also applies to homozygous familial hypercholesterolemia, or can be used with diet or other lipid-lowering means (such as LDL removal method) used alone.