C19H25BN4O4 CAS No. 179324-69-7 C19H25BN4O4
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Production information:
Product Name | Bortezomib |
CAS | 179324-69-7 |
MF | C19H25BN4O4 |
MW | 384.24 |
EINECS | 605-854-3 |
Melting point | 122-124°C |
Density | 1.214 |
storage temp. | -20°C |
Bortezomib[CAS:179324-69-7]
Appearance |
White to off-white powder |
|
Assay |
98~102% |
100.1% |
Melting Point |
175~185ºC |
179~182ºC |
Specific Rotation |
-45.0°~ -60° |
-56° |
Acidity Grade |
4.0~7.0 |
5.9 |
Loss on Drying |
≤ 1.5% |
0.83 |
Heavy Metal |
20ppm |
comfirmed |
LPS |
≤10EU/mg |
comfirmed |
Isomer |
BI01≤0.20% BI02≤0.20% BI03≤0.20% |
BI01:0.026% BI02:0.022% BI03: N.D |
Impurity
|
BI10≤0.2,BI07≤0.1, BI11≤0.15,BI08+BI09≤1.0%, BI05+BI04≤0.6,BIO6≤0.15%, BI12≤0.15,others each≤0.1%, Total≤2.5% |
BI08+BI09:0.02% BI12:0.012% All others: N.D Total impurity:0.045% |
Identification |
1HNMR,IR,MS,UV |
(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate CAS:179324-87-9
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