Osimertinib Mesylate CAS 1421373-66-1 Osimertinib

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10 Gram	Negotiable

10 Gram

Negotiable

Min.Order :10 Gram
Purity: >99%
Payment Terms : L/C,T/T,

Keywords

1421373-66-1 Osimertinib Osimertinib Mesylate

Quick Details

Appearance:white powder
Application:Pharmaceutical raw materials
PackAge:1kg/2kg/5kg aluminum foil/tin, 25kg/drum
ProductionCapacity:500 |Kilogram|Month
Storage:Cool Dry Place
Transportation:BY SEA OR BY AIR

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Details:

Osimertinib mesylate Basic information
Product Name:   Osimertinib mesylate
Synonyms:   AZD-9291 (Mesylate);N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);AZD-9291 mesylate N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);Osimertinib;N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt;Osimertinib Mesylate(AZD9291);Osimertinib mesylate;Mereletinib mesylate
CAS:   1421373-66-1
MF:   C28H33N7O2.CH4O3S
MW:   595.71298
EINECS:   200-064-1
Product Categories:   AZD09;API
Mol File:   1421373-66-1.mol
Osimertinib mesylate Structure
Osimertinib mesylate Chemical Properties

Description:

Osimertinib is active against exon 19 deletions, exon 21 mutations, and also the exon 20 T790M mutations. It is preferentially selective for mutated EGFR, and therefore toxicity at therapeutic doses is lower than for first- and second-generation agents. Notably, osimertinib is able to cross the blood-brain barrier, making it active against disease in the CNS.

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