72558-82-8 Ceftazidime C22H22N6O7S2
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Ceftazidime (Ceftazidime) is the third generation cephalosporin. The pneumococcus, Streptococcus and Staphylococcus aureus and gram positive bacteria was weaker than cefazolin; resistant to Staphylococcus aureus and Enterococcus methicillin ineffective against gram negative bacteria; just as powerful, such as good on Escherichia coli, Klebsiella pneumoniae, proteus, Sha Lei bacteria, bacillus, influenza Pseudomonas aeruginosa, Neisseria gonorrhoeae, meningococcal has antibacterial activity; gram positive anaerobic aerobic bark on Motoki Shinami, but the resistance of Bacteroides fragilis.
It is also used for the lower respiratory tract, skin and soft tissue, bone and joint, thoracic cavity, abdominal cavity, urogenital system and central infection caused by sensitive strains of Gram-negative bacteria. It is also used for septicemia.
Function
1.For pneumonia and lower respiratory tract infection caused by Gram-negative bacilli, intraperitoneal and biliary tract infections, complex urinary tract infections and severe skin and soft tissue infections, etc. It is especially suitable for immunodeficiency caused by multi-drug resistant Gram bacilli, nosocomial infection and infection of central nervous system caused by Gram-negative bacilli or Pseudomonas aeruginosa.
2. It is clinically used for general severe infections caused by sensitive bacteria (such as sepsis, meningitis, bacteremia), respiratory tract infections (such as pneumonia, bronchitis), ear, nose and throat infections, skin and soft tissue infections, urinary tract infections, gastrointestinal, biliary and abdominal infections, bone and joint infections, etc.
Product Name | Ceftazidime/Sodium Carbonate |
|
Shelf life | 2 years | |
ITEMS | SPECIFICATION | RESULT |
[Description] | A white or almost white crystalline powder | Almost white crystalline powder |
[Identification] |
(l)the retention time of which corresponds to that in the chromatogram of the CRS (2) It produces a white precipitate. |
In accordance with that of CRS
Complies |
pH | The pH should between 5.0 to 7.5 | 6.8 |
Loss on drying | NMT13.5% | 12.6% |
particulate matter | Meet the requirements | Complies |
Limit of Pyridine | NMT0.4% | 0.02% |
Bacterial endotoxins | Meet the requirement | Complies |
Sterility | Meet the requirements | Complies |
Assay | The content of Ceftazidime (C22H22N607S2) should not less than 90.0 per cent and not more than 105.0 per cent on the anhydrous and sodium carbonate
free basis The content of sodium carbonate is 8.0%~10.0° |
9.5% |
Conclusion:According to USP 32, the results meet the requirements. |
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