Roxithromycin CAS 8...

Roxithromycin CAS 80214-83-1

Roxithromycin CAS 80214-83-1

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: >99%
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Keywords

Roxithromycin 80214-83-1 C41H76N2O15

Quick Details

  • Appearance:white powder
  • Application: Roxithromycin, a western medicine, is a new generation of macrolide antibiotics, mainly acting on gram-positive bacteria, anaerobic bacteria, chlamydia and mycoplasma. Its antibacterial effect in
  • PackAge:1-5KG/Tin or Bag,25KG/Drum, 200KG/Drum
  • ProductionCapacity:1000 |Metric Ton|Year
  • Storage:Cool Dry Place
  • Transportation:by sea or by air

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Details:

Function:

Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.
1.Macrolide antibiotics, erythromycin derivatives, antibacterial spectrum and erythromycin similar, but the role of 6 times stronger than erythromycin, bioavailability. For respiratory infections such as pneumonia, acute bronchitis, acute exacerbation of chronic bronchitis, atypical pneumonia, and genitourinary infections, skin and soft tissue infections, have good therapeutic effect and tolerance, adverse reactions than erythromycin Small.
2. This product is a new generation of macrolide antibiotics, mainly for Gram-positive bacteria, anaerobic bacteria, chlamydia and mycoplasma. Its antibacterial activity in vitro and erythromycin similar to the role of the body stronger than erythromycin 1-4 times.
3. In clinical medicine for drug-resistant Staphylococcus aureus and hemolytic streptococcus caused by the preferred drug, veterinary clinical treatment of penicillin-resistant, Staphylococcus aureus caused by severe infections, pneumonia, metritis, chronic respiratory disease of fowls Wait.
4. Mainly used for the treatment of chronic respiratory disease in livestock and poultry, Staphylococcus aureus and streptococcal disease, chlamydia, spirochaetosis (swine dysentery), infectious pleurisy, rhinitis and so on.

Name of product Roxithromycin hcl
EXP. Time 3 years
Analysis content Analysis results Standard
Appearance White or almost white crystalline powder white crystalline powder
Identification 1) IR:  conforms to the Roxithromycin CRS specturm Meets the requirements
2) HPLC: Similar inreatention time and size to the principal peak of the reference solution conforms
Appearance of solution clear and colourless conforms
Specific Rotation between -93º-96º  -95º
Assay(HPLC) 99.69% 99.0~100%
Related substances 1) Impurity G% less than 1.0% 0.09%
  2) Impurity A,B,C,D,E,F,H,I,J less than 0.5% 0.31%
3)Total Impurities less than 3.0% 1.7%
Heavy metals less than 10ppm <10ppm
water less than 3.0% 2.2%
Sulphated ash less than 0.1% 0.02%
Residual solvents methanol less than 3000PPM 286PPM
acetone less than 5000ppm not detected
methylene chloride less than 600ppm not detected
Conclusion:  Complies with requirements of EP8.0

 

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