Weight Loss Raw Mat...

Weight Loss Raw Material Orlistat Powder CAS 96829-58-2 Treating Obesity Slimming

Weight Loss Raw Material Orlistat Powder CAS 96829-58-2 Treating Obesity Slimming

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: >99%
  • Payment Terms : L/C,T/T,

Keywords

96829-58-2 Orlistat C29H53NO5

Quick Details

  • Appearance:white powder
  • Application:Orlistat is in a class of medications called lipase inhibitors. It works by preventing some of the fat in foods eaten from being absorbed in the intestines. This unabsorbed fat is then removed from th
  • PackAge:1-5KG/Tin or Bag,25KG/Drum, 200KG/Drum
  • ProductionCapacity:1000 |Metric Ton|Year
  • Storage:Cool Dry Place
  • Transportation:by sea or by air

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Details:

Orlistat is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet. Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug. The effectiveness of orlistat in promoting weight loss is definite but modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2-3 kilograms (4.4-6.6 lb) more than those not taking the drug over the course of a year. Orlistat also modestly reduces blood pressure and appears to prevent the onset of type 2 diabetes, whether from the weight loss itself or to other effects. In a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.

Functions & Applications

Functions:

Orlistat capsula is in a class of drugs called lipase inhibitors. Orlistat capsula works in your intestines, where it blocks some of the fat you eat from being absorbed and digested. This undigested fat is then removed in your bowel movements .

 

Application:

1. As pharmaceutical raw materials 2. Health care products. 3. Orlistat capsula is used with a low-calorie diet to help you lose weight and to maintain your weight after weight loss.

Item Requirements Test Results
Appearance while to off-while powder White powder
Identification HPLC retention time Conforms
Melting Point 42 ºC -45°C 42°C-44°C
Specific optical rotation -31.0°~-41.0° -36.0°
Purity by HPLC no less than 98.0% 98.5%
Total impurity no more than 2.0% 1.6%
Max Individual impurity no more than 0.5% 0.3%
Water content%(K&F) no more than 0.5% 0.1%
Residual solvents EtOH no more than 0.5% N.D
EtAC no more than 0.5% N.D
nHeptane no more than 0.5% less than 0.1%
Residue on ignition less than 0.2% 0.10%
Assay (HPLC) no less than 98.0% 98.60%
Conclusion Meets the Requirements

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