Ozenoxacin Intermed...

Ozenoxacin Intermediate CAS 103877-51-6

Ozenoxacin Intermediate CAS 103877-51-6

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Ozenoxacin Intermediate 103877-51-6 C16h16clno3

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  • Appearance:white Powder
  • Application: Intermediates and materials
  • PackAge:1-5KG/Tin or Bag,25KG/Drum, 200KG/Drum
  • ProductionCapacity:1000 |Metric Ton|Year
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Product information

Product Name: ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate
Synonyms: ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate;ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate;ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate;7-Chloro-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid ethyl ester;7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate;3-Quinolinecarboxylic acid, 7-chloro-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-, ethyl ester;Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate fandachem;7- Chloro-1-cyclopropyl-8-methyl-4-oxyquinoline-3-carboxylate, ethyl ester
CAS: 103877-51-6
MF: C16H16ClNO3
MW: 305.76
EINECS: 600-496-4


Ozenoxacin is a new type of non-fluoroquinolone antibacterial drug developed by Ferrer for the treatment of pustular dermatitis and other skin infections. By inhibiting DNA gyrase and topoisomerase IV, it is used as a cream (10g , 1%) to treat bacterial skin infections, including Gram-positive skin and soft tissue infections. At present, the compound has successfully completed the Phase III clinical trials for the treatment of adult Chemicalbook and pustular dermatitis in children, showing stronger antibacterial activity, safety and tolerability. Ozefloxacin was launched in Japan in July 2014 and was approved in September 2015 for the treatment of acne and skin infections (10g, 2%, gel). Ozefloxacin has a long chemical synthesis route. In its synthesis process, the following compound is an important Ozefloxacin intermediate.
 


Product Name		 Ethyl 7-chloro-8-methyl-4-oxo-
1,4-dihydroquinoline-3-carboxylate		 CAS No.       103877-51-6

Batch No.		 19031501
Mfg. Date		 2019.03.15

Report Date		 2019.03.21
Exp. Date		 2021.03.14

Quantity		 800 g
Quality Standard
Enterprise Standard

Tests
SPECIFICATIONS
RESULTS

Appearance
White to  yellow powder
 Light yellow  powder

Related substances
Total impurities ≤2.0%		 1.189%

Max unknown single impurity ≤1.0%		 0.718%

loss on drying		 ≤1.0% 0.32%

Conclusion		 .
The results conform to the Enterprise standard

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