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Cefuroxime Axetil Cefuroxime 1-acetoxyethyl ester 64544-07-6
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Product Details
Treatment of infections of lower respiratory tract including pneumonia, urinary tract, skin and skin structures, bone and joints; treatment of bacteremia/septicemia, CNS infections, intra-abdominal infections including peritonitis, gynecological infections including pelvic inflammatory disease.
Application&Function
Cefuroxime axetil is applicable to hemolytic streptococcus, Staphylococcus aureus (methicillin-resistant strains except), and Haemophilus influenzae, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, etc. caused by susceptible strains of Enterobacteriaceae adults with acute pharyngitis or tonsillitis, acute otitis media, maxillary sinusitis, acute exacerbation of chronic bronchitis, acute bronchitis, uncomplicated urinary tract infections, skin and soft tissue infections and no complications Neisseria gonorrhoeae urethritis and cervicitis. Children pharyngitis or tonsillitis, acute otitis media and impetigo, etc.
Product name | Cefuroxime axetil | ||
Packing | 20kgs/drum | Batch Size | 200kgs |
Standard | USP42 | ||
Contents | Specification | Results | |
Characters | White or almost powder | Conforms | |
Identification | IR | Conforms | |
HPLC | Conforms | ||
Crystalline | Amorphous | Conforms | |
Diastereoisomer ratio | 0.48-0.55 | 0.54 | |
Water | ≤1.5% | 0.26% | |
Organic impurities | Methoxyiminofuranyl acetic acid a ≤0.30% | Not detected | |
Cefuroxime b ≤0.50% | Not detected | ||
Cefuroxime lactone c≤0.30% | Not detected | ||
Cefuroxime axetil △-3isomersd,e≤1.20% | Not detected | ||
Cefuroxime axetil E-isomersd, f.≤1.00% | 0.18% | ||
Cefuroxime axetil dimerg.h≤0.50% | Not detected | ||
Any other individual impurity≤0.30% | Not detected | ||
Total impurites≤3.0% | 0.18% | ||
Assay | 745-875ug/mg | 836ug/mg | |
Conclusion: It complies with the requirements of the USP42 |
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