Tylosin Tartrate Po...

Tylosin Tartrate Powder Granule Tylosin CAS 63428-13-7 with low price

Tylosin Tartrate Powder Granule Tylosin CAS 63428-13-7 with low price

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: >99%
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Keywords

Tylosin Acetylisovaleryltylosin Tartrate 63428-13-7

Quick Details

  • Appearance:white powder
  • Application: For pharmaceutical
  • PackAge:1-5KG/Tin or Bag,25KG/Drum, 200KG/Drum
  • ProductionCapacity:1000 |Metric Ton|Year
  • Storage:Cool Dry Place
  • Transportation:by sea or by air

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Details:

Basic information

Product Name: Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate
Synonyms: Tylosin, 3-acetate 4B-(3-methylbutanoate), (2R,3R)-2,3-dihydroxybutanedioate (salt);Acetylisovaleryltylosin Tartrat;Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate;Acetylisovaleryltylosin Tartrate;Aivlosin Tartrate;Tylvalosin Tartrate;(2S,3S,4R,6S)-6-(((2R,3S,4R,5R,6R)-6-(((4R,5S,6S,7R,9R,11E,13E,15R,16R)-4-acetoxy-16-ethyl-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl)oxy)-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (2R,3R)-2,3-dihydroxysuccinic acid;(2R,3R,4R,5R,6R)-6-(((2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-5-Acetoxy-4-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl)methoxy)-4,5-dimethoxy-2-methyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (2R,3R)-2,3-dihydroxysuccinate
CAS: 63428-13-7
MF: C57H93NO25
MW: 1192.34002
EINECS: 256-145-7


Tylvalosin Tartrate, formerly known as acetylisovaleryl tylosin (TAT), is a macrolide antibiotic. The mechanism of action is the same as that of other macrolide antibiotics. It can bind to the nucleoprotein body 50S subunit of Chemicalbook of sensitive bacteria, and inhibit the synthesis and elongation of peptide chain by blocking the transpeptidation and/or mRNA displacement, and affect the synthesis of bacterial protein.

Function of Tylvalosin Tartrate
Tylvalosin Tartrate has antibacterial activity against a variety of Gram-positive bacteria, such as Staphylococcus, Micrococcus, Microbacteria, Bacillus, Corynebacterium, Aerococcus, Campylobacter, Enteric Chemicalbook Coccus, Streptococcus, Arthrobacter and Clostridium Bacteria, etc.; it also has good antibacterial activity against mycoplasma, and works better at high concentrations; but it has no effect on most Gram-negative bacteria.

Specification

Items Standards  Results Conclusions 
Appearance White powder or pale white powder.  White powder Complies
Identification (1) Wave length (nm) Max.Absorbace290nm aqueous solution. (1)Wavelength(nm)Max. Absorbance 290nm Complies
(2)Dissolved in acetone, by addition of hydrochloric acid, the solution gradually turns from light yellow to dark purple. (2)Positive Complies
(3)Dissolved in water, by addition of silver nitrate solution, yield white precipitation; separating the precipitation and which can be dissolved in nitric acid.. (3)Positive Complies
(4)By TLC method, the sample should show the same dominant color spot as the reference standard at the same position at 254nm. (4)Complies Complies
Solubility Stir 1.0mg of powder with 300ml water by mechanical stirrer for 10 minutes, then wait for 30 minutes until the solution become completely clear. Complies Complies
Acidity pH value 3.0-5.0 pH value 4.1 Complies
Tyramine Sample absorbance not more than that of reference substance at 570nm. Sample absorbance lower than reference substance at 570nm. Complies
Active constituent Content of acetylisovaleryl tylosin A is not less than 80%. 88% Complies
Loss on drying Weight loss is not more than 4.0%. 1.00% Complies
Heavy metals Heavy metal content is not more than 20ppm. <20ppm Complies
Potency The potency of 1 milligram sample is not less than 800U of acetylisovaleryl tylosin on the dried basis. 884U/mg Complies
Conclusion:Product in compliance with standards


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