CasNo.54965-24-1,Tamoxifen Citrate Powder,(54965-24-1) Suppliers

10 Gram	FOB Price:USD 20.0000 -45.0000

Min.Order :10 Gram
Purity: 99%
Payment Terms : T/T,,MoneyGram

Keywords

Tamoxifen Citrate Nolvadex 54965-24-1

Quick Details

Appearance:White crystalline powder
Application:It can be used as pharmaceutical material
PackAge:Aluminum foil bag/hidden
ProductionCapacity:1000|Kilogram|Day
Storage:Shading, confined preservation
Transportation:FedEx,DHL,EMS, special line delivery

Superiority:

1. Quality

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the pharmaceutical area and every batch of steroid powders have to be

tested by our QC (quality control) before steroids are allowed to sell.

2. Delivery

Mass stock for steroids, so we could be able to pack your powders

within 24 hours after your payment confirmed, and the corresponding

picture of your powders' parcel will be sent to you. The lead time within 15 days.

3. Package

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4. Payment

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5. Price

The best prices you're sure to be satisfied with, the more you buy, the more competitive prices you will get.

Details:

Basic Information:

Product Name:Tamoxifen citrate Nolvadex

English synonyms:

tamoxifene;terimon;trans-1-(p-beta-dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-enecitrate;y-1,2,3-propanetricarboxylate(1:1);z-tamoxifencitrate;Z-1-(P-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE;[Z]-1-[P-DIMETHYLAMINOETHOXYPHENYL]-1,2-DIPHENYL-1-BUTENE CITRATE SALT;(z)-2-[4-(1,2-diphenyl-1-butenyl)phenoxyl]-n,n-dimethyl-ethanamine-citrate

CAS Number:54965-24-1

MF:C32H37NO8

MW:563.64

EINECS:259-415-2

Mol File:54965-24-1.mol

Properties:

Melting Point:140-144 °C

Appearance:White crystalline powder

Applications and synthesis methods

1.Sumarry

Tamoxifen citrat e (TCT) is a competitive antagonist of estrogen. It is a non-steroidal anti-estrogen drug. It can compete with estradiol in vivo and combine with estrogen receptor of breast cancer cells, thus inhibiting the effect of estrogen on cancer cells. The growth and development of tumor cells are blocked, and the anti-cancer effect is exerted. Clinically, it is often used to treat various types of breast cancer, especially for postmenopausal breast cancer patients with positive estrogen receptor and progesterone receptor and low level of prostate specific antigen.

2. clinical application

(1) Treatment of breast cancer.

(2) Prevention of breast cancer.

(3) Anti-tumor and anti-multidrug resistance. Tamoxifen citrate can inhibit or hinder the growth and metastasis of cancer cells by reducing membrane fluidity and enhancing the rigidity of cell-to-cell binding sites, reducing the concentration and activity of cancer metastasis promoters and various activating enzymes. In addition, it can also stimulate the cells around the tumor focus to secrete negative growth factor-transforming growth factor-TGF-G, inhibit the unlimited proliferation of cancer cells, and inhibit the oxidative damage of DN A base caused by hydrogen peroxide produced by human neutrophils, so it can be used for the treatment and pre-treatment of malignant tumors other than breast cancer. Prevention is beneficial and has been used in the treatment of brain tumors, liver cancer, prostate cancer and other cancers. In addition, tamoxifen citrate can reduce the release of P170 glycoprotein on cell membrane by reducing the membrane fluidity, increase the effective concentration of cytotoxic drugs in cells and reduce drug resistance.

(4) Heart protection.