DL-Mevalonolactone 674-26-0 98% purity
Product Name: DL-Mevalonolactone
Synonyms: DL-MEVALONOLACTONE;β-Hydroxy-β-methyl-δ-valerolactone, (±)-β-Hydroxy-β-methyl-δ-valerolactone, (±)-3-Hydroxy-3-methyl δ-valerolactone, (±)-Mevalolactone, (±)-Mevalonic acid lactone, (±)-Mevalonolactone;(4S)-4-Hydroxy-4-methyltetrahydro-2H-pyran-2-one;(S)-3,5-Dihydroxy-3-methylpentanoic acid δ-lactone;(S)-4β-Hydroxy-4-methyltetrahydro-2H-pyran-2-one;(S)-Tetrahydro-4-hydroxy-4-methyl-2H-pyran-2-one;Beta-Hydro;(±)-Mevalonolactone,(±)-β-Hydroxy-β-methyl-δ-valerolactone, (±)-3-Hydroxy-3-methyl δ-valerolactone, DL-Mevalolactone, DL-Mevalonic acid lactone
CAS: 674-26-0
MF: C6H10O3
MW: 130.14
EINECS: 211-615-0
Mol File: 674-26-0.mol
Melting point 28 °C(lit.)
alpha -1.0~+1.0°(20℃/D)(c=5, C2H5OH)
Boiling point 145-150 °C5 mm Hg(lit.)
density 1.1066 (rough estimate)
refractive index n20/D 1.473(lit.)
Fp >230 °F
storage temp. -20°C
pka 13.57±0.20(Predicted)
Merck 14,6163
BRN 80960
Stability: Hygroscopic
InChIKey JYVXNLLUYHCIIH-UHFFFAOYSA-N
CAS DataBase Reference 674-26-0(CAS DataBase Reference)
NIST Chemistry Reference Dl-mevalonic acid lactone(674-26-0)
Safety Information
WGK Germany 3
F 3-10
HS Code 29322090
MSDS Information
Provider Language
SigmaAldrich English
DL-Mevalonolactone Usage And Synthesis
Chemical Properties Pale Yellow Oil
Uses A metabolite from endophytes of the medicinal plant Erythrina crista-galli.
Uses HMG CoA substrate
Synthesis Reference(s) Journal of the American Chemical Society, 104, p. 5486, 1982 DOI: 10.1021/ja00384a040
Synthesis, p. 719, 1974 DOI: 10.1055/s-1974-23416
Purification Methods Purify the lactone via the dibenzyl-ethylenediammonium salt (m 124-125o) [Hofmann et al. J Am Chem Soc 79 2316 1957], or by chromatography on paper or on a Dowex-1 (formate) column. [Bloch et al. J Biol Chem 234 2595 1959.] Store it as the N,N'-dibenzylethylenediamine (DBED) salt, or as the lactone in a sealed container at 0o. [Beilstein 18/1 V 19.]
DL-Mevalonolactone Preparation Products And Raw materials
Preparation Products 3-METHYLPENTANE-1,3,5-TRIOL
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