3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE 127842-54-0 98% purity
Product Name: 3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE
Synonyms: Benzaldehyde, 3,4-bis(difluoroMethoxy)-;Roflumilast Impurity K;3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE
CAS: 127842-54-0
MF: C9H6F4O3
MW: 238.14
EINECS: 1312995-182-4
Mol File: 127842-54-0.mol
3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE Chemical Properties
Boiling point 265.8±35.0℃ (760 Torr)
density 1.387±0.06 g/cm3 (20 ºC 760 Torr)
Fp 111.1±20.8℃
storage temp. Inert atmosphere,2-8°C
Safety Information
MSDS Information
3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE Usage And Synthesis
Chemical Properties Yellow Oil
Uses 3,4-Bis(difluoromethoxy)benzaldehyde is an impurity of the antiasthmatic drug Roflumilast (R639700). 3,4-Bis(difluoromethoxy)benzaldehyde is used in the preparation of diphenylethylene compounds as PDE4 (phosphodiesterase-4) inhibitors for treatment of cancer, CNS disorders, and inflammatory disorders.
3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE Preparation Products And Raw materials
Raw materials 4-Difluoromethoxy-3-hydroxybenzaldehyde-->Difluorochloromethane-->Protocatechualdehyde
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