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O-Phosphocolamine Phosphorylethanolamine 1071-23-4
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Product information
Phosphorylethanolamine or phosphoethanolamine is an ethanolamine derivative that is used to construct two different categories of phospholipids. One category termed a glycerophospholipid and the other a sphingomyelin, or more specifically within the sphingomyelin class, a sphingophospholipid. This chemical possesses two pKa[clarification needed] values: 5.61 and 10.39.
Function
The ethanolamin e mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain.It can be used to synthesize and treat brain diseases.
Application
1. An experiment with mice that stated synthetic phosphoethanolamine has in vitro and in vivo anti-leukemia effects.
2. As a potential drug, phosphorylethanolamine in undergoing human clinical trials.The main synthetic form of phosphorylethanolamine is calcium 2-aminoethylphosphate.
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