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Valnemulin Hydrochloride Valnemulin 133868-46-9
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Product information
Valnemulin Hydrochloride is a broad spectrum antibiotic used to control gastrointestinal infections in animals, and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA.
Function
Valnemulin hydrochloride mechanism of action is to inhibit the synthesis of bacterial proteins at the
ribosome level, and to inhibit the synthesis of RNA at high concentrations. It is mainly antibacterial, but it is
also sterilized at high concentrations. The antibacterial spectrum is wide and effective for G + and
G-bacteria, and it is highly effective for molds and spirals, while it is less effective for intestinal bacteria
such as E. coli and Salmonella.
Uses
Hydrochloride salt Valnemulin, semisynthetic antibiotic; derivative of pleuromutilin. Antibacterial.
Valnemulin hydrochloride is the salt prepared from valnemulin taking advantage of the basic amino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Valnemulin is a broad spectrum antibiotic used to control gastrointestinal infections in animals, and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA.
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