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5 Kilogram |
FOB Price: USD 280.0000 |
33818-15-4 Wholesaler 33818-15-4 reasonable price Citicoline sodium factory
Wholesaler Citicoline sodium factory 33818-15-4
Cell phosphorus choline is a nucleic acid derivative, geiger in 1956 in animal tests found that cytophosphocholine can restore brain damage; It is currently the best-selling drug for the treatment of brain diseases and plays an important role in the synthesis of lecithin, improving brain function by promoting the synthesis of lecithin. Experiments show that cytophocholine can enhance the levels of norepinephrine and dopamine in the central nervous system, thus treating cerebrovascular disease, traumatic brain injury and cognitive impairment caused by various causes, with no obvious side effects.White crystalline or crystalline powder at room temperature, odorless, soluble in water, insoluble in ethanol, acetone, chloroform
A solvent-assisted mechanochemical approach to access symmetrical and mixed dinucleoside 5,5′-polyphosphates is reported. Under ball-milling conditions, nucleoside 5′-monophosphates were quantitatively activated using 1,1′-carbonyldiimidazole, forming their phosphorimidazolide derivatives. The addition of a nucleoside 5′-mono-, di- or triphosphate directly led to the formation of the corresponding dinucleotides.
Benefits of the reported one-pot method include the use of unprotected nucleotides in their sodium or acid form, activation by the eco-friendly 1,1′-carbonyldiimidazole, non-dry conditions, short reaction time, high conversion rates, and easy setup and purification. This work offers new perspectives for the synthesis of nucleotide conjugates and analogues, combining the phosphorimidazolide approach and milling conditions.
【Product name】Citicoline Sodium
【Synonyms】Cytidine 5'-diphosphocholine monosodium salt
Cytidine 5'-diphosphocholine sodium salt dihydrate
【CAS No.】33818-15-4
【Mol. Formula】 C14H25N4NaO11P2
【Mol. Weight】 510.31
【Standard】 CP2015 Part II
【Assay】≥98.0%
【Appearance】 White powder or crystalloid powder
【Character】 Odorless and little bitter
【Packing】 25kgs/drum (standard packing)
【Storage】 Tight container, protect from light
Citicoline Sodium, also known as cytidine diphosphate-choline & cytidine 5'-diphosphocholine. It is an intermediate in the generation of phosphatidylcholine from choline. Citicoline powder is a precursor of phosphatidylcholine. As a type of phospholipid, phosphatidylcholine is an important component of cell membranes. Studies suggest that citicoline supplements help improve focus and mental energy and may possibly be useful in the treatment of attention deficit disorder.
Quality Standard
Item |
Specifications |
Appearance |
White powder or crystalloid powder |
Assay |
≥98.0% |
PH |
6.0-7.5 |
Clarity and color of solution |
Clarifying,colorcless |
Clorides |
≤0.05% |
Ammonium |
≤0.05% |
Iron |
≤0.01% |
Phosphate |
≤0.1% |
5'-CMP |
≤0.3% |
The other largest impurities |
≤0.2% |
The other total impurities |
≤0.7% |
Methanol |
≤0.3% |
Ethanol |
≤0.5% |
Acetone |
≤0.5% |
Loss on drying |
≤6.0% |
Heavy metals |
≤10ppm |
Arsenic |
≤0.0001% |
Bacterial Endotoxins |
≤0.3EU/mg |
Function
Citicoline sodium can enhance the function of brain stem reticular formation, especially the ascending reticular activating system associated with human consciousness; enhance the function of the pyramidal system; inhibit the function of the external system of the cone, and promotes the recovery of the function of the system. For the treatment of sequelae of traumatic brain injury and cerebral vascular accident caused by the nervous system, it can also be used in the treatment of Parkinson's disease, senile dementia has a certain effect; for the treatment of cardiovascular and cerebrovascular diseases; it also have a certain effect for anti-aging, improving learning and memory.
Shanghai Soyoung Biotechnology Inc. a faithful and professional supplier and exporter of healthcare raw materials for pharmacy, nutrition and food industries for years with own laboratory and GMP standard factories.
Shanghai Soyoung has R&D Center and Testing Center, and has international advanced facilities of HPLC, GC, AAS, UV, TLC, LC-MS and IR equipments.
Shanghai Soyoung has nearly 20 years production experience, it is producing in GMP workshop, each batch pass strict testing before shipment. Strict quality control is performed in every procedure from material sourcing, processing and testing to packing.
Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many years, with own laboratories and GMP standard factories.
1. 10+years specialized in health products field.
2. GMP/ISO certificated factories and stable supply chain.
3. Quality first, strictly control before shipments.
4. Custom synthesis by more than 20 professional chemists.
5. Small order,free sample and one step service available.
6. Rapid delivery, 1-6 business days from China warehouse.
7. Support 7 days refund money in case delay shipment.
8. Assessment conducted by Bureau Veritas at 2018.
FAQ:
Q1:Will you supply samples for testing
A: samples for the quality evaluation for most products, but customers need to undertake the shipping fee for delivery the samples to your door.
Q2:What's your MOQ
A: For the high value product, our MOQ starts from 10g,100g and 1kg.
Q3:Which kind of payment terms do you accept
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by bitcoin,usdt,xmr,west union
Q4:How about your delivery time
A: Generally, it will take 3 to 5 days after receiving your advance payment.
Q5:How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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