CasNo.486460-32-6,High Quality 99% Sitagliptin phosphate monohydrate,(486460-32-6) Suppliers

1 Kilogram	FOB Price:USD 25.0000 -800.0000

Min.Order :1 Kilogram
Purity: 99% up
Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

Keywords

Sitagliptin Powder factory price High purity 99%

Quick Details

Appearance:White powder
Application:Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
PackAge:1kg/bag ;5kg/drum:25KG/drum
ProductionCapacity:20|Metric Ton|Month
Storage:in low tempreture
Transportation:in low tempreture

Superiority:

Why is SINOWAY:

1) Specialized in pharmaceutical and healthcare industrial for 34 years.

2) ISO 9001:2015 & SGS audited supplier .

3) Accept various payment terms : T.T 30-60 days.

4) We have warehouse in USA with quickly shipment .

5) We can do different terms of FOB ,CIF/CIP ,DDP ...

Why choose us

1. best quality in your requirement
2. competitive price in china market
3. mature technical support
4. professional logistic support
5. full experience of large numbers containers loading in chinese sea port
6. fast shipment by reputed shipping line
7. packing with pallet as buyer's special request
8. best service after shipment with email !
9. cargoes together with container after-sales service available
10. full experience in export
11. raw materials from chinese origin

Details:

Product Information

product Name	Sitagliptin
Molecular Formula	C₁₆H₁₅F₆N₅O
Molecular Weight	407.3136
InChI	InChI=1/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m0/s1
CAS Registry Number	486460-32-6;790712-60-6
Molecular Structure
Density	1.614g/cm³
Boiling point	529.905°C at 760 mmHg
Refractive index	1.59
Flash point	274.277°C
Vapour Pressur	0mmHg at 25°C

Function

Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Application

An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
Sitagliptin phosphate monohydrate should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis, as it would not be effective in these settings.
Sitagliptin phosphate monohydratehas not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at increased risk for the development of pancreatitis while using Sitagliptin phosphate monohydrate.

Specification

Appearance	White or almost White powder	White powder
Solubility	Easy to dissolve in the water	Complies
Identification	High -performance liquid chromatograph HPLC	Almost the same
Identification	Infrared absorption	Almost the same
Melting point	203.0-205.0ºC	204.0~205.0ºC
Chiral impurity:	≤1.0%	0.4%
Related Impurities:	Total Impurities ≤1.0%	0.63%
Water	≤1.0%	0.6%
Heavy metals	≤20ppm	<20ppm
Residue on ignition	≤0.1%	0.01 %
Specific Rotation	Between -18.0 °and 23.0°	-21.05°
HPLC Assay	98.0% ~ 102.0%	99.5%