cytarabine 147-94-4 C9H13N3O5
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White fine needle-like crystals or crystalline powder. Soluble in water, partly soluble in methanol, almost insoluble in ether, it is made from D-arabinose or 5′-cytosine nucleotide. Its hydrochloride is commonly used. Melting point: 214℃ It is an anti-pyrimidine antimetabolite, which can inhibit DNA polymerase, interfere with nucleotide participation in DNA, and inhibit nucleotide reductase, block the reduction of cytosine nucleotide to deoxycytosine nucleotide, but has no significant effect on RNA and protein synthesis.
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