497-76-7 Arbutin Beta arbutin
Beta arbutin CAS No:497-76-7 Whitening agent
Name: Beta arbutine
Synonym: Arbutine; beta-arbutin ; 4-hydroxyphenyl β-D-galactopyranoside
Chemical name: 4-Hydroxyphenyl-beta-D-glucopyranoside
CAS No: 497-76-7
Property: Arbutin effectively inhibits formation of melanin, splash and fleck can be got ride of and no side effects are caused.
Arbutin can also moisten the skin which looks very lightening, so arbutin is used skin lightening and whitening agents in the cosmetics. Arbutin was also used as a drug.
Specification:
Appearance:White needle-like crystal or crystalline powder
Melting Point :199-201 ± 0.5℃
PH of 1% water solution :5.0 - 7.0
Specific optical rotation : -66 ± 2°
IPV: 1515 cm-1 1220cm-1 1050cm-1 ± ( 5- 8 cm-1 )
Arsenic: ≤ 2 ppm
Hydroquinone: ≤ 10 ppm
Heavy Metals : ≤ 10 ppm
Loss on drying : ≤ 0.5%
Residue on ignition : ≤ 0.5%
Pathogen Bacteria:≤ 300cfu/g
Fungus: ≤ 100cfu/g
Assay : ≥ 99.5%
Application:
1. Arbutin is easy to decompose in acidic environment, pay attention to the pH value of the system is controlled above 6.0
2. when used, should be dissolved in a small amount of water at 45 ° C, after the cream is completely emulsified at 45 ° C
3. should Add appropriate amount of antioxidants such as sodium bisulfite for formula system;
4. when formulated, can be effectively compatible with zwitterionic surfactants and anionic surfactants;
5. adding natural vegetable oil containing oleic acid, linoleic acid, Promote the synergistic effect of Arbutin;
6. azone, octadecyl dimethylamine oxide, etc. can promote the absorption of Arbutin;
7. Dosage: 2 ~ 7%.
Package: Net weight 1.0kg/aluminum foil bag , 10 aluminum foil bags/carton or 25kg / drum.
Storage: should store in cool, dry conditions in well sealed containers.
Wuhan BJM Pharm Inc. was found in 2013, located in Hubei Province, where has long history, rich culture, convenient traffic, beautiful environment and preferential policy.
We have two factories in Dezhou , Shandong and Xianning, Hubei. The factory covers an area of 48,000 square meters with the building area of 26,000 square meters. We are specialized in the manufacture of pharmaceutical intermediates and cosmetic additives with good inspection equipments and innovative R & D capability.
In 2006, We established Lingxian Microworld Chemical New Material Co,.Ltd.
In 2008, We passed ISO quality system certificate
In 2013, We established Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd , and obtain self-operation Import & Export right, mainly responsible for domestic and foreign business. At the same time, we set up R&D lab in Wuhan,Hubei province, can undertake various custom synthesis of intermediates and APIs.
In 2016, obtain a registered trademark “ BJM ”.
In 2017, we applied for the invention patent of TRIS, and in 2018, we applied for the invention patent of ERDOSTAN intermediate(DL-HOMO). At present, we have6 patents passed the preliminary examination, and 4 patents are under examination and approval.
In 2019, we purchased a R&D and office building with a total area of 2500 square meters, as our headquarters in Wuhan.
In 2020, we registered BJM Pharm Yunmeng Co., Ltd, and the new production base settled in Geputan chemical park with a total area of 50000 square meters.
We are specialized in the R&D ,production and sales of Erdosteine ,Pirfenidone, Telmisartan, Letrozole , Sitagliptin phosphate, Dapagliflozin , Tris , IPTG and related intermediates.
We stick to the principle as: people-oriented, customer first, Hope to establish a win-win business relationship with all friends.
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