What are the advantages of carbomer as a medicinal excipient?

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What are the advantages of carbomer as a medicinal excipient Carbomer has been highly praised in the pharmaceutical field since it was first applied in the 1950s. Carbomer has been widely used in the research and production of cosmetics and drugs abroad, and has been included in the Pharmacopoeia of many countries, but it is still a relatively new material in China. It has many uses in drug punishment. For example, it can be used as a disinfectant gel, Carbomer Eye Drops, Carbomer, drug delivery adhesive, Carbomer skin disinfectant gel, and controlled release material. What advantages does carbomer have as pharmaceutical excipients

Carbomer can be used as ophthalmic gel. At present, the common eye drops used in clinic are short of drug retention in the eyes, resulting in poor drug absorption. However, Carbomer is different. It not only does not have the above shortcomings, but also clinically it can alleviate the symptoms of dry eyes caused by endocrine disorders and insufficient tear production, reduce inflammation and treat presbyopia. The new bromide eye drops used in the treatment of dry eye disease in clinic is effective because of its short contact time with cornea. Instead, the gel made with carbomer has a significant effect on promoting weeping, and it will produce the greatest effect after 1 hours.

In addition to the ingredients of ophthalmic gel, in the oral protein polypeptides drug delivery system, the use of carbomer bags can increase the adhesive time of milk droplets and intestinal mucosa around the milk drops. The microemulsion containing carbomer 940 can increase the intestinal absorption of drugs such as desmopressin. At the same time, the protease inhibition and absorption promotion of carbomer are also conducive to increase the absorption of drugs.

Carbomer 940 is used as the excipient of topical drugs. It is not only easy to apply, but also absorbs tissue solution, which is conducive to the discharge of secretions. It has good stability, smooth and comfortable skin feeling, easy cleaning and good air permeability. Some oral drugs are made into gel through skin, and become topical drugs, which reduces the stimulation of internal organs. When used for external use on the skin, Carbomer also has moisturizing property, can lubricate the skin, protect the skin from pollution and irritation, and has anti infection effect.

It should be noted that carbomer is used as a pharmaceutical excipient and does not have any other drug effects. It is used as gel, thickener, dispersant or suspending agent as a carrier medium for medicine. Desheng is a professional manufacturer of carbomer. Its products mainly include carbomer 980 and carbomer 940, and customers respond very well. Carbomer, as a new polymer material and excellent pharmaceutical excipients, will play a certain role in promoting the use of new excipients and the research of new preparations in China.