157283-68-6 Travoprost C26H35F3O6
Tests |
Specifications |
Results |
Appearance |
Colorless to yellowish viscous oily liquid |
Yellowish viscous oily liquid |
Identification |
|
|
By TLC |
The Travoprost should be appear as Black Spots. |
Conforms |
By HPLC |
The Retention time of the maior peak in the chromatogram of the test preparation corresponding to that in the chromatogram of the standard preparation, as per Assay test. |
Conforms |
Specific Rotation |
[α]20D: +52.0° ~ +58.0°at 365nm |
55.3° |
Water |
N.M.T.1.0 % |
0.2% |
Limit of ethyl acetate |
N.M.T. 5000ppm |
1400ppm |
Travoprost Related compound A |
N.M.T. 0.2% |
N.D. |
15-epi Diasteromer |
N.M.T. 0.5% |
0.18% |
5,6-trans Isomer |
N.M.T. 3.5% |
0.80% |
15-Keto derivative |
N.M.T. 0.3% |
N.D. |
Any other impurity |
N.M.T. 0.1% |
0.09% |
Total impurities |
N.M.T. 4.0% |
1.2% |
Assay: Travoprost |
96.0% ~ 102%(C26H35F3O6) |
98.4% |
Conclusion |
Conform to USP37 |
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