Ethambutol

Ethambutol

Ethambutol

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 98% purity
  • Payment Terms : T/T,Other

Keywords

Ethambutol 74-55-5 98% purity

Quick Details

  • Appearance:powder
  • Application:intermediate
  • PackAge:According to the need of packing
  • ProductionCapacity:100|Kilogram|Month
  • Storage:Keep in dark place,Sealed in dry,2-8°C
  • Transportation:air,sea,courier

Superiority:

Product Name:    Ethambutol
Synonyms:    ETHAMBUTOL;(+)-2,2-(Ethylenediimino)di-1-butanol;(+)-2,2’-(ethylenediimino)di-1-butanol;(+)-n,n’-bis(1-(hydroxymethyl)propyl)ethylenediamine;(+)-s,s-ethambutol;(r)-2,2’-(1,2-ethanediyldiimino)bis-1-butanol;2,2’-(1,2-ethanediyldiimino)bis-,(r-(r*,r*))-1-butano;2’-(1,2-ethanediyldiimino)bis-(r)-1-butano
CAS:    74-55-5
MF:    C10H24N2O2
MW:    204.31
EINECS:    200-810-6
Product Categories:    
Mol File:    74-55-5.mol
 

Details:

Melting point     199-204℃
alpha     D25 +13.7° (c = 2 in water)
Boiling point     345℃
density     1.0048 (rough estimate)
refractive index     1.4610 (estimate)
RTECS     EL3640000
Fp     >110°(230°F)
storage temp.     Keep in dark place,Sealed in dry,2-8°C
pka    pKa 6.6 (H2O) (Uncertain);9.5(H3O) (Uncertain)
Water Solubility     Soluble in water. Also soluble in chloroform and methylene chloride
Safety Information
Hazardous Substances Data    74-55-5(Hazardous Substances Data)
Toxicity    LD50 oral in rat: 998mg/kg

Originator    Myambutol,Lederle,US,1967
Uses    Antibacterial.
Uses    Ethambutol is an antitubercular antibiotic.
Definition    ChEBI: An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial d ug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant str ins of M. tuberculosis are readily produced if ethambutol is used alone.
Indications    Ethambutol is a water-soluble, heat-stable compound that acts by inhibition of arabinosyl transferase enzymes that are involved in cell wall biosynthesis. Nearly all strains of M. tuberculosis and M. kansasii and most strains of Mycobacterium avium-intracellulare are sensitive to ethambutol. Drug resistance relates to point mutations in the gene (EmbB) that encodes the arabinosyl transferases that are involved in mycobacterial cell wall synthesis.

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