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75330-75-5 Lovastatin Antihypercholesterolemic Antifungal
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Product name: | Lovastatin |
CAS: | 75330-75-5 |
Chemical Properties: | White Solid |
Molecular Formula: | C24H36O5 |
Molecular Weight: | 404.54 |
Uses: | An antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase antiarrhythmic Lovastatin (mevinolin) is a metabolite first isolated from Monascus ruber and later found in several other fungal species. Lovastatin is a potent inhibitor of HMG-CoA. HMG-CoA reductase is the rate-controlling enzyme of the mevalonate pathway, responsible for the biosynthesis of cholesterol. Lovastatin was developed as a drug as a hypolipemic agent. anti-hyperlipoproteinemic, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor |
Biological Activity | Potent, competitive inhibitor of HMG-CoA reductase (K i = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo . Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro . |
USAGE:
1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE was used as a pharmaceutical intermediateitor
Product Name | Tert-Butyl 4- (4-fluoroanilino) |
CAS | 288573-56-8 |
Molecular formula | C16H23FN2O2 |
Molecular Weight | 294.36400 |
Boiling point | 92-96 oC (0.6 Torr) |
Flash point | 110.9±21.8 oC |
Melting Point | 58.5-59.0 oC |
PSA | 41.57000 |
LogP | 3.64800 |
Appearance | Light yellow crystalline powder |
Accurate quality | 294.17400 |
Packing | Aluminum foil bag or as your requirement |
Usage | Mainly use in Pharmaceutical Intermediates/medical intermediate/ Research purpose |
Type | Pharmaceutical Intermediates |
Storage | The warehouse is ventilated, low temperature and dry, and stored separately from food materials |
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